1272031-47-6Relevant articles and documents
Synthesis of highly enantioenriched C-TERTIARY amines from boronic esters: Application to the synthesis of igmesine
Bagutski, Viktor,Elford, Tim G.,Aggarwal, Varinder K.
supporting information; experimental part, p. 1080 - 1083 (2011/04/21)
Better than all the rest: Tertiary boronic esters, readily available using the lithiation-borylation reaction, have been converted into tertiary alkylamines in very high ee. The work has been applied to a short, modular, and fully stereocontrolled synthesis of the pharmaceutical igmesine and chiral 2,2-disubstituted piperidines.