127244-78-4

Basic information

• Product Name: 2-bromo-6-(4-nitrophenylethoxy)purine
• Synonyms: 2-bromo-6-(4-nitrophenylethoxy)purine
• CAS NO: 127244-78-4
• Molecular Weight: 364.158
• Mol File: 127244-78-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-bromo-6-(4-nitrophenylethoxy)purine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-6-(4-nitrophenylethoxy)purine(127244-78-4)
• EPA Substance Registry System: 2-bromo-6-(4-nitrophenylethoxy)purine(127244-78-4)

Safety Data

• Hazardous Substances Data: 127244-78-4(Hazardous Substances Data)

Upstream product

• 100-27-6 2-(4-nitrophenyl)ethanol 
• 87781-93-9 2-bromo-1,9-dihydro-6H-purin-6-one 
• 76-83-5 trityl chloride 

Downstream Products

• 127218-16-0 Acetic acid (2R,3R,4R,5R)-4-acetoxy-5-acetoxymethyl-2-{2-bromo-6-[2-(4-nitro-phenyl)-ethoxy]-purin-9-yl}-tetrahydro-furan-3-yl ester 
• 120033-37-6 9-<5'-deoxy-2',3'-di-O-benzoyl-5'-(diethoxyphosphinyl)-β-D-ribofuranosyl>-2-bromohypoxanthine 
• 120033-38-7 9-<5'-deoxy-2',3'-di-O-benzoyl-5'-(diethoxyphosphinyl)-β-D-ribofuranosyl>hypoxanthine 
• 3181-38-2 2',3',5'-tri-O-acetylinosine 
• 118-00-3 G 
• 58-63-9 Inosine 
• 41623-91-0 2-bromo-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)hypoxanthine 
• 127211-14-7 2-Bromo-6-[2-(4-nitro-phenyl)-ethoxy]-9-trimethylsilanyl-9H-purine 

Relevant articles and documents

An Efficient Regioselective Synthesis of Substituted Purine Analogues of Guanosine and Inosine

Condensation of 2-bromo-6-(4-nitrophenylethoxy)purine as the trimethylsilyl derivative (5a) with 1,2,3,5-tetra-O-acetyl-β-D-ribofuranose, 1-O-acetyl-2,3-di-O-benzoyl-5-deoxy-5-diethoxy-phosphinyl-β-D-ribofuranose, and (2-acetoxyethoxy)methyl bromide resulted in N9-regioselective alkylation to give (6a-c), which were then converted to guanine and hypoxanthine nucleosides, nucleotides, and Acyclovir analogues, respectively.