1273558-75-0

Basic information

• Product Name: 2-(2-bromo-4-methylphenyl)-1H-benzo[d]imidazole
• Synonyms: 2-(2-bromo-4-methylphenyl)-1H-benzo[d]imidazole
• CAS NO: 1273558-75-0
• Molecular Weight: 287.159
• Mol File: 1273558-75-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-(2-bromo-4-methylphenyl)-1H-benzo[d]imidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-bromo-4-methylphenyl)-1H-benzo[d]imidazole(1273558-75-0)
• EPA Substance Registry System: 2-(2-bromo-4-methylphenyl)-1H-benzo[d]imidazole(1273558-75-0)

Safety Data

• Hazardous Substances Data: 1273558-75-0(Hazardous Substances Data)

Upstream product

• 95-54-5 1,2-diamino-benzene 
• 7697-27-0 2-bromo-4-methylbenzoic acid 
• 824-54-4 2-bromo-4-methylbenzaldehyde 

Downstream Products

• 1254070-49-9 C₁₇H₁₅BrN₂ 
• 1449011-50-0 1-(2-aminophenyl)-2-(2-bromo-4-methylphenyl)benzimidazole 
• 1449011-42-0 2-(2-bromo-4-methylphenyl)-1-(2-nitrophenyl)benzimidazole 
• 1174039-97-4 3-methyl-6-phenylbenzo[4,5]imidazo[2,1-a]isoquinoline 

Relevant articles and documents

Synthesis of Trinuclear Benzimidazole-Fused Hybrid Scaffolds by Transition Metal-Free Tandem C(sp2)?N Bond Formation under Microwave Irradiation

2-(2-Bromoaryl)- and 2-(2-bromovinyl)benzimidazoles have been coupled and cyclized with 2-methoxy- and 2-aryloxybenzimidazoles as building blocks in the presence of a base under microwave irradiation to give a class of trinuclear N-fused hybrid scaffolds, benzo[4,5]imidazo[1,2-a]benzo[4,5]imidazo[1,2-c]quinazolines and -pyrimidines, respectively, in good yields. 2-(2-Bromoaryl)- and 2-(2-bromovinyl)imidazoles also reacted with 2-methoxybenzimidazoles in the presence of base under microwave irradiation to give a class of trinuclear N-fused hybrid scaffolds, benzo[4,5]imidazo[1,2-a]imidazo[1,2-c]quinazolines and -pyrimidines, respectively, in similar yields. This process seems to proceed via an initial C(sp2)-N coupling by an addition-elimination nucleophilic aromatic substitution (SNAr) and subsequent cyclization accompanied by extrusion of alcohols.

Expeditious synthetic approach and photophysical properties of fluorescent benzimidazo[1,2-d]dibenzo[b,f][1,4]diazepine derivatives

A short and efficient synthetic route to novel benzimidazo[1,2-d]dibenzo[b, f][1,4]diazepines has been developed using a copper catalyzed intramolecular Ullmann type C-N bond forming reaction as a key step. Copper iodide and 1,10-phenanthroline furnished the desired compounds in good yield. The products are intensely fluorescent with appreciably long lifetimes. Looking at their prospective use as markers for biomacromolecules and in biochemical analysis, we have explored the photophysical properties of these compounds. The spectrophotometric and spectrofluorometric studies reveal that while the absorbance maxima of the compounds are in the UV region, the emission maxima fall in the visible (blue-green) region.