127356-16-5

Basic information

• Product Name: 2,3-Pyridinediamine,4-methoxy-(9CI)
• Synonyms: 2,3-Pyridinediamine,4-methoxy-(9CI);2,3-Diamino-4-methoxypyridine;4-methoxypyridine-2,3-diamine
• CAS NO: 127356-16-5
• Molecular Formula: C₆H₉N₃O
• Molecular Weight: 139.16
• Product Categories: PYRIDINE
• Mol File: 127356-16-5.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 335.1±37.0 °C(Predicted)
• Appearance: /
• Density: 1.251±0.06 g/cm3(Predicted)
• PKA: 7.76±0.47(Predicted)
• CAS DataBase Reference: 2,3-Pyridinediamine,4-methoxy-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-Pyridinediamine,4-methoxy-(9CI)(127356-16-5)
• EPA Substance Registry System: 2,3-Pyridinediamine,4-methoxy-(9CI)(127356-16-5)

Safety Data

• Hazardous Substances Data: 127356-16-5(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of Medicinal Chemistry, 33, p. 2231, 1990 DOI: 10.1021/jm00170a030

Upstream product

• 84487-08-1 4-methoxy-3-nitro-pyridin-2-ylamine 
• 6980-08-1 4-chloro-3-nitro-2-pyridinamine 
• 19798-80-2 2-Amino-4-chloropyridine 
• 1072-97-5 5-bromo-2-pyridylamine 
• 84249-02-5 2-nitroamino-4-bromopyridine 
• 84487-10-5 2-amino-4-bromo-3-nitropyridine 

Downstream Products

• 127356-20-1 7-Methoxy-2-(2-methoxy-4-methylsulfanyl-phenyl)-1H-imidazo[4,5-b]pyridine 
• 127356-03-0 2-(4-Methanesulfinyl-2-methoxy-phenyl)-7-methoxy-1H-imidazo[4,5-b]pyridine 
• 1426833-17-1 1-(2-chloro-phenyl)-6-methoxy-4-methyl-2,3,5,9,9b-pentaazacyclopenta[a]naphthalene 
• 1426824-69-2 N-[1-(2-chloro-phenyl)-methylidene]-N'-(8-methoxy-2-methyl-pyrido[2,3-b]pyrazin-3-yl)-hydrazine 
• 1426833-18-2 1-(2-chloro-6-methyl-phenyl)-6-methoxy-4-methyl-2,3,5,9,9b-pentaazacyclopenta[a]naphthalene 
• 1426833-19-3 1-(2,6-bismethyl-phenyl)-6-methoxy-4-methyl-2,3,5,9,9b-pentaazacyclopenta[a]naphthalene 

Relevant articles and documents

Polycyclic compound for inhibiting RNA helicase DHX33

The invention relates to a polycyclic compound for inhibiting RNA helicase DHX33. In particular, the invention relates to a compound shown as a formula I or a pharmaceutically acceptable form thereof, a pharmaceutical composition containing the compound, a preparation method of the compound, and medical application of the compound to prevention and/or treatment of DHX33 related diseases.

A model D - amino acid oxidase inhibitor and its preparation and application

The invention provides a novel D- amino acid oxidase inhibitor and a preparation and application thereof. In particular, the invention discloses derivatives of quinoxaline-2,3-diketone, which has a novel structure shown in formula A, as well as a preparation method thereof and an application as an inhibitor of D-amino acid oxidase (DAAO). The compound provided by the invention shows excellent effects of analgesia and blocking morphine analgesia tolerance, and has application value for analgesia, treating opiate drug tolerance, and anti-schizophrenia.

PYRIDINE COMPOUNDS AND USES THEREOF

The present invention is directed to pyridine compounds of Formula (I). Separate aspects of the invention are directed to pharmaceutical compositions comprising said compounds and uses of the compounds as therapeutic agents treating neurological and psych