1274795-53-7

Basic information

• Product Name: 2,2,2-trichloro-N-((1R,5R)-5-isopropyl-2-methylcyclohex-2-enyl)acetamide
• Synonyms: 2,2,2-trichloro-N-((1R,5R)-5-isopropyl-2-methylcyclohex-2-enyl)acetamide
• CAS NO: 1274795-53-7
• Molecular Weight: 298.64
• Mol File: 1274795-53-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2,2,2-trichloro-N-((1R,5R)-5-isopropyl-2-methylcyclohex-2-enyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,2-trichloro-N-((1R,5R)-5-isopropyl-2-methylcyclohex-2-enyl)acetamide(1274795-53-7)
• EPA Substance Registry System: 2,2,2-trichloro-N-((1R,5R)-5-isopropyl-2-methylcyclohex-2-enyl)acetamide(1274795-53-7)

Safety Data

• Hazardous Substances Data: 1274795-53-7(Hazardous Substances Data)

Upstream product

• 499-71-8 carvotanacetone 
• 536-30-1 (+)-cis-(1S,5S)-5-isopropyl-2-methyl-2-cyclohexen-1-ol 

Downstream Products

• 1274795-58-2 methyl (1R,5R)-5-isopropyl-2-methylcyclohex-2-enylcarbamate 
• 1274795-59-3 C₁₄H₂₅NO₃ 
• 1274795-60-6 C₁₈H₂₇NO₄ 
• 1274795-61-7 C₂₀H₂₉NO₅ 
• 1561030-12-3 (3aR,6R,7aR,E)-3-(4-hydroxybutylidene)-6-isopropyl-1,3a-dimethyl-3,3a,7,7a-tetrahydro-1H-indol-2(6H)-one 
• 1561029-86-4 (3aR,6R,7aR,E)-6-isopropyl-3-(4-(4-methoxybenzyloxy)butylidene)-1,3a-dimethyl-3,3a,7,7a-tetrahydro-1H-indol-2(6H)-one 
• 1561029-84-2 (Z)-2-bromo-N-((1R,5R)-5-isopropyl-2-methylcyclohex-2-enyl)-6-(4-methoxybenzyloxy)-N-methylhex-2-enamide 
• 1561029-79-5 (1R,5R)-5-isopropyl-N,2-dimethylcyclohex-2-enamine 

Relevant articles and documents

Asymmetric synthesis of the tricyclic core of calyciphylline A-type alkaloids via intramolecular [3 + 2] cycloaddition

Asymmetric synthesis of the [5-6-7] tricyclic system common to the Calyciphylline A-type alkaloids is reported, featuring Overman rearrangement, Heck cyclization, intramolecular [3 + 2] cycloaddition, diastereoselective hydrogenation, and Claisen rearrangement as strategic events. The approach is capable of installing the crucial carbonyl functionality as well as multiple stereogenic centers within a congested polycyclic ring skeleton.