127598-83-8Relevant articles and documents
First example of the cascade acylation/IMDAV/ene reaction sequence, leading to N-arylbenzo[f]isoindole-4-carboxylic acids possessing anti-viral activity
Voronov, Alexander A.,Alekseeva, Kseniia A.,Ryzhkova, Elena A.,Zarubaev, Vladimir V.,Galochkina, Anastasia V.,Zaytsev, Vladimir P.,Majik, Mahesh S.,Tilve, Santosh G.,Gurbanov, Atash V.,Zubkov, Fedor I.
supporting information, p. 1108 - 1111 (2018/03/06)
The reaction between readily accessible N-aryl-3-phenylallylamines and maleic anhydride led to unexpected products – polysubstituted hydrogenated benzo[f]isoindole-4-carboxylic acids. This transformation proceeds through a previously unknown sequence of s
Air Stable Iron(II) PNP Pincer Complexes as Efficient Catalysts for the Selective Alkylation of Amines with Alcohols
Mastalir, Matthias,St?ger, Berthold,Pittenauer, Ernst,Puchberger, Michael,Allmaier, Günter,Kirchner, Karl
, p. 3824 - 3831 (2016/12/16)
A series of well-defined iron(II) complexes of the types [Fe(PNP)Br2] and [Fe(PNP)(CO)Br2] with PNP pincer ligands based on triazine and pyridine backbones were prepared and fully characterized. These complexes were tested as catalysts for the alkylation of amines by alcohols. The high-spin complexes [Fe(PNP)Br2] are catalytically inactive. The low-spin complexes [Fe(PNP)(CO)Br2] bearing a carbonyl co-ligand efficiently and selectively convert primary alcohols and aromatic and benzylic amines selectively into mono-N-alkylated amines in good to excellent isolated yields. A mechanistic proposal is given. (Figure presented.).
Solvent-free synthesis, DNA-topoisomerase II activity and molecular docking study of new asymmetrically N,N′-substituted ureas
Andressa, Esteves-Souza,Rodrigues-Santos, Claudio E.,De Nigris Del Cistia, Catarina,Da Silva, Daniel Rosa,Sant'Anna, Carlos Mauricio R.,Echevarria, Aurea
, p. 12882 - 12894 (2013/02/22)
A new series of asymmetrically N,N′-substituted ureas 20-25 was prepared using solvent free conditions, which is an eco-friendly methodology, starting with Schiff bases derived from cinnamaldehyde and p-substituted anilines, which are subsequently submitt