127676-18-0 Usage
Description
2-(5-ethyl-2-pyridyl)propane-1,3-diol is an organic compound characterized by its unique molecular structure, which features a pyridyl group attached to a propane-1,3-diol backbone. This structure endows the compound with specific chemical and physical properties that make it suitable for various applications across different industries.
Uses
Used in Pharmaceutical Industry:
2-(5-ethyl-2-pyridyl)propane-1,3-diol is used as an impurity in the production of Pioglitazone (P471000), an antidiabetic drug. Its presence in the manufacturing process is essential for the development of the final product, which aids in managing blood sugar levels in patients with diabetes.
Used in Chemical Synthesis:
2-(5-ethyl-2-pyridyl)propane-1,3-diol can be utilized as a building block or intermediate in the synthesis of more complex organic compounds. Its unique structure allows for further functionalization and modification, making it a valuable component in the development of new pharmaceuticals, agrochemicals, or other specialty chemicals.
Used in Research and Development:
Due to its distinctive chemical properties, 2-(5-ethyl-2-pyridyl)propane-1,3-diol can be employed in research and development settings to study various chemical reactions and mechanisms. It may also be used to investigate the effects of structural modifications on the properties and reactivity of related compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 127676-18-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,6,7 and 6 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 127676-18:
(8*1)+(7*2)+(6*7)+(5*6)+(4*7)+(3*6)+(2*1)+(1*8)=150
150 % 10 = 0
So 127676-18-0 is a valid CAS Registry Number.
127676-18-0Relevant articles and documents
Development of an improved and scalable process for 2-(5-ethylpyridin-2-yl) ethan-1-ol: Solvent-free reaction and recycling of the starting material 5-ethyl-2-picoline
Mohanty, Sandeep,Talasila, Srinivasarao,Roy, Amrendra Kumar,Karmakar, Arun Chandra
, p. 168 - 173 (2014/05/20)
The main objective of this exercise was to develop a more efficient process for 2-(5-ethylpyridin-2-yl)ethan-1-ol (1), which is the key intermediate in the synthesis of pioglitazone hydrochloride. This process not only features the yield improvement of (1) by optimizing reaction variables in solvent-free conditions but also highlights improving the mass efficiency of 5-ethyl-2-picoline (2), thereby reducing the effluent load per kilogram of the intermediate.
