1277186-39-6

Basic information

• Product Name: C₂₀H₁₃BrN₄O₂
• Synonyms: C₂₀H₁₃BrN₄O₂
• CAS NO: 1277186-39-6
• Molecular Weight: 421.253
• Mol File: 1277186-39-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₀H₁₃BrN₄O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₀H₁₃BrN₄O₂(1277186-39-6)
• EPA Substance Registry System: C₂₀H₁₃BrN₄O₂(1277186-39-6)

Safety Data

• Hazardous Substances Data: 1277186-39-6(Hazardous Substances Data)

Upstream product

• 1047640-39-0 3-aminonaphtho[2,1-b]furan-2-carboxylic acid hydrazide 
• 233-00-1 naphtho[1,2-d]isoxazole 
• 7470-09-9 2-hydroxy-1-naphthaldehyde oxime 
• 847200-28-6 ethyl 3-amino-naphtho[2,1-b]furan-2-carboxylate 
• 34844-82-1 (1-cyano-naphthalen-2-yloxy)-acetic acid ethyl ester 
• 52805-47-7 1-cyano-2-hydroxynaphthalene 
• 1277186-34-1 C₂₀H₁₅BrN₄O₂S 

Relevant articles and documents

Synthesis of biologically active-3-amino-2-(1,3,4-oxadiazolyl, 1,3,4-thiadiazolyl and 1,2,4-triazolyl) naphtho [2,1-0] furans

Hydroxynaphthonitrile (4), was prepared by cyclizing hydroxynaphthaldoxime (3). The compound (4) was reacted with ethyl chloroacetate to get a condensed product (5) which was cyclized into ethyl 3-aminonaphtho [2,1-6] furan-2-carboxylate (6). The treatment of ester (6) with hydrazine hydrate resulted in the formation of hydrazide (7), where it was further condensed with various isothiocyanates to get 3-aminonaphtho [2,1-b] furan (e-arylamino)-2- carbothiosemicarbazides (8a-e). The semicarbazides 8 were cyclized into title compounds using different methods. The newly synthesized compounds were characterized by analytical and spectral data. They were subjected to the antimicrobial screening. Some of them gave encouraging activity.