127759-67-5 Usage
Description
(1R,2R)-BIS[TERT-BUTYL(PHENYL)PHOSPHINO]ETHANE, also known as (R,R)-Ph-BPE, is a chiral diphosphine ligand used in organometallic and coordination chemistry. It consists of two tert-butyl groups and two phenyl groups attached to a central ethane backbone, with phosphorus atoms at the ends of the molecule. (1R,2R)-BIS[TERT-BUTYL(PHENYL)PHOSPHINO]ETHANE acts as a powerful chelating ligand and is characterized by its chiral nature, which allows for the synthesis of enantioenriched molecules.
Uses
Used in Asymmetric Catalysis:
(1R,2R)-BIS[TERT-BUTYL(PHENYL)PHOSPHINO]ETHANE is used as a chelating ligand for asymmetric catalysis, particularly in the hydrogenation of various substrates and other organic transformations. Its chiral nature enables the synthesis of enantioenriched molecules, making it a valuable tool in the field of asymmetric synthesis and chemical research.
Used in Chemical Research:
(1R,2R)-BIS[TERT-BUTYL(PHENYL)PHOSPHINO]ETHANE is used as a research tool in chemical research for the development of new organometallic complexes and coordination compounds. Its unique structure and properties contribute to the advancement of knowledge in organometallic and coordination chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 127759-67-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,7,5 and 9 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 127759-67:
(8*1)+(7*2)+(6*7)+(5*7)+(4*5)+(3*9)+(2*6)+(1*7)=165
165 % 10 = 5
So 127759-67-5 is a valid CAS Registry Number.
127759-67-5Relevant articles and documents
Synthesis and reactions of phosphine-boranes. Synthesis of new bidentate ligands with homochiral phosphine centers via optically pure phosphine-boranes
Imamoto, Tsuneo,Oshiki, Toshiyuki,Onozawa, Takashi,Kusumoto, Tetsuo,Sato, Kazuhiko
, p. 5244 - 5252 (2007/10/02)
Secondary and tertiary phosphine-boranes were synthesized in one-pot from phosphine oxides or substituted chlorophosphines without isolation of the intermediate phosphines. Phosphine-boranes having a methyl group were metalated with sec-butyllithium. The generated carbanions reacted with alkyl halides or carbonyl compounds to yield various phosphine-borane derivatives. The carbanions underwent copper(II)-promoted oxidative coupling without impairment of the borane functionality. Secondary phosphine-boranes reacted with alkyl halides, aldehydes, or α,β-unsaturated carbonyl compounds to give phosphine-borane derivatives having a functional group. The boranato group of phosphine-boranes was removed in a stereospecific manner with retention of configuration by treatment with a large excess of amine such as morpholine. A new route to bidentate ligands with homochiral phosphine centers has been explored by utilizing these characteristic reactivities of phosphine-boranes. Thus, optically pure (S,S)-1,2-bis(o-anisylphenylphosphino)ethane, (R,R)-1,2-bis(tert-butylphenyl-phosphino)ethane, and (S,S)-1,4-bis(o-anisylphenylphosphino)butane have been synthesized via phosphine-boranes.