127818-75-1

Basic information

• Product Name: 10-DODECENOICACID
• Synonyms: 10-DODECENOICACID
• CAS NO: 127818-75-1
• Molecular Formula: C12H22O2
• Molecular Weight: 198.30188
• Mol File: 127818-75-1.mol
• Article Data: 3

Chemical Properties

• Melting Point: 9.63°C (estimate)
• Boiling Point: 321.28°C (estimate)
• Appearance: /
• Density: 0.9176 (rough estimate)
• Refractive Index: 1.4426 (estimate)
• CAS DataBase Reference: 10-DODECENOICACID(CAS DataBase Reference)
• NIST Chemistry Reference: 10-DODECENOICACID(127818-75-1)
• EPA Substance Registry System: 10-DODECENOICACID(127818-75-1)

Safety Data

• Hazardous Substances Data: 127818-75-1(Hazardous Substances Data)

Usage

General Description

10-Dodecenoic acid, also known as alpha-dodecenoic acid, is an unsaturated fatty acid with a 12-carbon chain and a double bond located at the 10th carbon. It is a colorless liquid with a slight odor and is insoluble in water. This chemical is commonly found in various natural sources such as animal fats and vegetable oils. It is often used as a precursor in the synthesis of flavors and fragrances, as well as in the production of dodecyl alcohol and dodecyl acetate. 10-Dodecenoic acid also exhibits biological activity and may have potential applications in pharmaceuticals and cosmetic products due to its antibacterial and anti-inflammatory properties.

Upstream product

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Relevant articles and documents

Structural requirements of dictyopyrones isolated from Dictyostelium spp. in the regulation of Dictyostelium development and in anti-leukemic activity

Cellular slime molds are fascinating to the field of developmental biology, and have long been used as excellent model organisms for the study of various aspects of multicellular development. We have recently isolated α-pyronoids, named dictyopyrones A-D (1-4), from various species of Dictyostelium cellular slime molds, and it was shown that compound 3 may regulate Dictyostelium development. In this study, we synthesized dictyopyrones A-D (1-4) and their analogues, investigated the physiological role of the molecules in cell growth and morphogenesis in D. discoideum, and further verified their effects on human leukemia K562 cells. Nitrogen-containing compounds 22 and 37 strongly inhibited cell growth in K562 leukemia cells, indicating that these compounds may be utilized as novel lead compounds for anti-leukemic agents.

Novel acyl α-pyronoids, dictyopyrone A, B, and C, from Dictyostelium cellular slime molds

For the elucidation of the diversity of secondary metabolites of Dictyostelium cellular slime molds, we investigate the constituent of three species of slime molds. From the methanol extract of their fruit bodies, we obtained three novel compounds, dictyopyrone A (1) and B (2) from D. discoideum and D. rhizoposium and dictyopyrone C (3) from D. longosporum. They possess a unique α-pyrone moiety with a side chain at the C-3 position. Their relative structures were elucidated by spectral means, and the absolute configuration was confirmed by asymmetric synthesis of 1. Since these compounds were obtained from different species of Dictyostelium slime molds, they may be a type of compound common to this genus.