127840-15-7

Basic information

• Product Name: 2-hydroxydodecyl 4-methylbenzenesulfonate
• CAS NO: 127840-15-7
• Molecular Weight: 356.527
• Mol File: 127840-15-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-hydroxydodecyl 4-methylbenzenesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-hydroxydodecyl 4-methylbenzenesulfonate(127840-15-7)
• EPA Substance Registry System: 2-hydroxydodecyl 4-methylbenzenesulfonate(127840-15-7)

Safety Data

• Hazardous Substances Data: 127840-15-7(Hazardous Substances Data)

Upstream product

• 1119-87-5 dodecane-1,2-diol 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 127840-17-9 Acetic acid (R)-1-(toluene-4-sulfonyloxymethyl)-undecyl ester 
• 127911-71-1 (2S)-2-hydroxydodecyl 4-methylbenzenesulfonate 
• 85514-85-8 (2S)-dodecane-1,2-diol 
• 109856-85-1 (R)-1,2-epoxydodecane 
• 130404-09-0 (2S)-1,2-epoxydodecane 

Relevant articles and documents

Synthesis of linear aza and thio analogues of acetogenins and evaluation of their cytotoxicity

We report the stereoselective synthesis of thio and aza analogues of Annonaceous acetogenins. The synthetic route allows easy variation of the stereochemistry and of the thio- and aza-fragments. Kinetic resolution of terminal bis-epoxides was used to set two remote stereocentres with high enantio- and diastereoselectivities in one step. The cytotoxicity of the analogues was assessed using the HeLa cell line. Four aza and two thio analogues of Annonaceous acetogenins were synthesized according to a general synthetic route. Two remote stereocentres in the analogues were set with high enantio- and diastereoselectivity in one step by hydrolytic kinetic resolution of a terminal bis-epoxide. Copyright