1278416-40-2

Basic information

• Product Name: 10-benzyl-2-(2-chlorophenyl)-2,3,8, 9,10,11-hexahydro-1H-pyrazolo[4',3':3,4]pyrido[1,2-a][1,4]diazepine-1,5(7H)-dione
• Synonyms: 10-benzyl-2-(2-chlorophenyl)-2,3,8, 9,10,11-hexahydro-1H-pyrazolo[4',3':3,4]pyrido[1,2-a][1,4]diazepine-1,5(7H)-dione
• CAS NO: 1278416-40-2
• Molecular Weight: 420.898
• Mol File: 1278416-40-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 10-benzyl-2-(2-chlorophenyl)-2,3,8, 9,10,11-hexahydro-1H-pyrazolo[4',3':3,4]pyrido[1,2-a][1,4]diazepine-1,5(7H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 10-benzyl-2-(2-chlorophenyl)-2,3,8, 9,10,11-hexahydro-1H-pyrazolo[4',3':3,4]pyrido[1,2-a][1,4]diazepine-1,5(7H)-dione(1278416-40-2)
• EPA Substance Registry System: 10-benzyl-2-(2-chlorophenyl)-2,3,8, 9,10,11-hexahydro-1H-pyrazolo[4',3':3,4]pyrido[1,2-a][1,4]diazepine-1,5(7H)-dione(1278416-40-2)

Safety Data

• Hazardous Substances Data: 1278416-40-2(Hazardous Substances Data)

Upstream product

• 13910-48-0 N-benzyl-1,3-diaminopropane 
• 1278416-72-0 methyl [(4Z)-4-(4-benzyl-1,4-diazepan-2-ylidene)-1-(2-chlorophenyl)-5-oxo-4,5-dihydro-1H-pyrazol-3-yl]acetate 
• 1350522-88-1 methyl [4-(chloroacetyl)-1-(2-chlorophenyl)-5-hydroxy-1H-pyrazol-3-yl]acetate 
• 1158233-60-3 methyl [1-(2-chlorophenyl)-5-hydroxy-1H-pyrazol-3-yl]acetate 
• 10449-07-7 (2-chlorophenyl)hydrazine 
• 1830-54-2 3-oxopentanedioic acid dimethyl ester 

Downstream Products

• 1350522-73-4 10-benzyl-2-(2-chlorophenyl)-2,3,8,9,10,11-hexahydro-1H-pyrazolo[4',3':3,4]pyrido[1,2-a][1,4]diazepine-1,5(7H)-dione hydrochloride 

Relevant articles and documents

Design, synthesis and biological activity of original pyrazolo-pyrido- diazepine, -pyrazine and -oxazine dione derivatives as novel dual Nox4/Nox1 inhibitors

Pyrazolo-pyrido-diazepine, -pyrazine and -oxazine dione derivatives are new chemical entities with good and attractive druglikeness properties. A series of pyrazolo-pyrido-diazepine dione analogs demonstrated to be particularly amenable to lead optimizati

Pyrazoline dione derivatives as nadph oxidase inhibitors

The present invention is related to pyrazoline dione derivatives of Formula (I), pharmaceutical composition thereof and to their use for the treatment and/or prophylaxis of disorders or conditions related to Nicotinamide adenine dinucleotide phosphate oxidase (NADPH Oxidase).