127940-66-3

Basic information

• Product Name: Cyclohexene, 1-(chloromethyl)-4-(1-methylethenyl)-
• CAS NO: 127940-66-3
• Molecular Formula: C10H15Cl
• Molecular Weight: 170.682
• Mol File: 127940-66-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Cyclohexene, 1-(chloromethyl)-4-(1-methylethenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexene, 1-(chloromethyl)-4-(1-methylethenyl)-(127940-66-3)
• EPA Substance Registry System: Cyclohexene, 1-(chloromethyl)-4-(1-methylethenyl)-(127940-66-3)

Safety Data

• Hazardous Substances Data: 127940-66-3(Hazardous Substances Data)

Upstream product

• 127-91-3 (1R,5R)-(+)-β-pinene 
• 138-86-3 limonene. 
• 177698-19-0 Beta-pinene 
• 536-59-4 (-)-perillyl alcohol 
• 536-59-4 perillol 

Downstream Products

• 5989-54-8 (-)-(S)-limonene 

Relevant articles and documents

Catalytic allylic chlorination of natural terpenic olefins using supported and nonsupported lewis acid catalysts

A mild and convenient method for the allylic chlorination of naturally occurring terpenic olefins was investigated in the presence of different supported and non-supported Lewis acid catalysts. The reaction has been tested on carvone as a model substrate in the presence of sodium hypochlorite as chlorine donor. The scope and limitations of transition metal-based Lewis acid catalysts, stoichiometry, and substrate structure were evaluated. Among the iron precursors used, FeCl3 and FeCl2 provide the promise of a general approach to allylic or vinylic chlorination reaction. Various terpenic olefins were examined in the presence of FeCl3/ NaOCl combination system. The catalytic chlorination proceeds under mild conditions with short reaction time and shows a high selectivity affording the corresponding chlorides in good to excellent yields.

CeCl3/NaClO: A safe and efficient reagent for the allylic chlorination of terminal olefins

The preparation of allylic chlorides by reaction of terminal olefins with sodium hypochlorite in the presence of cerium trichloride heptahydrate is described. The scope, limitations and synthetic perspectives of the reaction are discussed.

Compounds which inhibit complement and/or suppress immune activity

The present invention is directed to compounds which suppress immune responses and/or selectively inhibit complement. These compounds contain an aromatic ring and are substituted dihydrobenzofurans, spirobenzofuran-2(3H)-cycloalkanes, and their open chain intermediates. The compounds of the present invention, and the pharmaceutically acceptable salts thereof, interrupt the proteolytic processing of C5 to bioactive components, exhibit immunosuppressive activities, and have therapeutic utility in the amelioration of disease and disorders mediated by complement and/or immune activity.