127945-26-0

Basic information

• Product Name: tert-butyl (1-methyl-3-piperidinyl)methyl malonate
• Synonyms: tert-butyl (1-methyl-3-piperidinyl)methyl malonate
• CAS NO: 127945-26-0
• Molecular Weight: 271.357
• Mol File: 127945-26-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl (1-methyl-3-piperidinyl)methyl malonate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (1-methyl-3-piperidinyl)methyl malonate(127945-26-0)
• EPA Substance Registry System: tert-butyl (1-methyl-3-piperidinyl)methyl malonate(127945-26-0)

Safety Data

• Hazardous Substances Data: 127945-26-0(Hazardous Substances Data)

Upstream product

• 7583-53-1 1-methyl-3-hydroxymethylpiperidine 
• 40052-13-9 mono-tert-butyl malonate 

Relevant articles and documents

Antibiotics from Gliding Bacteria, XLII. Chemical Modification of Sorangicin A and Structure - Activity Relationship I: Carboxyl and Hydroxyl Group Derivatives

The synthesis of selectively protected sorangicin A derivatives and their application in the modification of the hydroxyl groups and the carboxyl group in sorangicin A (1) is described.Esters, amides, and sorangicins modified at the hydroxyl groups were prepared and their activities against Staphylococcus aureus, Escherichia coli, and their in vitro inhibition of RNA polymerase were examined.Although no sorangicin A derivatives with superior biological activity were observed, some derivatives completely retained their antibiotic activity or were slightly improved in their activity with certain strains.