127958-64-9

Basic information

• Product Name: Hexahydro-2H-benzo[b][1,4]oxazin-3(4H)-one
• Synonyms: Hexahydro-2H-benzo[b][1,4]oxazin-3(4H)-one;Hexahydro-2H-1,4-benzoxazin-3(4H)-one
• CAS NO: 127958-64-9
• Molecular Formula: C₈H₁₃NO₂
• Molecular Weight: 155
• Mol File: 127958-64-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 351℃
• Flash Point: 166℃
• Appearance: /
• Density: 1.092
• CAS DataBase Reference: Hexahydro-2H-benzo[b][1,4]oxazin-3(4H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: Hexahydro-2H-benzo[b][1,4]oxazin-3(4H)-one(127958-64-9)
• EPA Substance Registry System: Hexahydro-2H-benzo[b][1,4]oxazin-3(4H)-one(127958-64-9)

Safety Data

• Hazardous Substances Data: 127958-64-9(Hazardous Substances Data)

Usage

General Description

Hexahydro-2H-benzo[b][1,4]oxazin-3(4H)-one, also known as morpholin-3-one, is a chemical compound with the molecular formula C7H11NO2. It is a heterocyclic organic compound that contains a six-membered ring with oxygen and nitrogen atoms. Hexahydro-2H-benzo[b][1,4]oxazin-3(4H)-one has applications in organic synthesis and pharmaceuticals, and it is often used as a building block in the production of various drugs and pharmaceutical compounds. It has a wide range of uses in the pharmaceutical industry, including as an intermediate in the synthesis of various drugs and as a key component in the production of certain medications. Additionally, it is also utilized in various chemical reactions and processes due to its unique structure and properties. Overall, hexahydro-2H-benzo[b][1,4]oxazin-3(4H)-one has important applications in the field of organic chemistry and pharmaceuticals.

Upstream product

• 95628-91-4 rac-trans-N-(2'-Hydroxycyclohexyl)-2-chloroacetamide 
• 105-36-2 ethyl bromoacetate 
• 931-16-8 (+/-)-trans-2-aminocyclohexanol 

Downstream Products

• 134961-97-0 rac-trans-2-carboxymethoxycyclohexylammonium chloride 
• 134961-98-1 trans-2-(2'-acetylaminocyclohexyloxy)acetic acid 
• 134961-99-2 trans-2-(2'-methylsulfonylaminocyclohexyloxy)acetic acid 
• 134962-00-8 trans-2-(2'-ethylsulfonylaminocyclohexyloxy)acetic acid 
• 134962-04-2 trans-2-(2'-t-butyloxycarbonylaminocyclohexyloxy)acetic acid 
• 134962-02-0 trans-2-<2'-(N'-phenylureido)cyclohexyloxy>acetic acid 
• 134962-03-1 trans-2-<2'-(N'-phenylthioureido)cyclohexyloxy>acetic acid 
• 134962-01-9 trans-2-(2'-tosylaminocyclohexyloxy)acetic acid 
• 142034-79-5 (1R,2R)-2-Carbomethoxycyclohexylammonium chloride 
• 74572-19-3 (±)-(4aR*,8aR*)-octahydro-2H-1,4-benzoxazine 

Relevant articles and documents

A concise and efficient synthesis of substituted morpholines

A simple and efficient method has been developed for the synthesis of substituted morpholines by a sequence of coupling, cyclization, and reduction reactions of easily available amino alcohols and α-halo acid chlorides. Various mono-, di-, and trisubstituted morpholines, spiro morpholines, and ring-fused morpholines, as well as morpholine homologues, were synthesized in good to excellent yields by a single methodology under similar reaction conditions. The method was also used in a multigram synthesis of (3S)-3-methylmorpholine.

Preparation of diastereomerically pure immunologically active carbocyclic nor-muramyldipeptide analogues

The preparation of diastereomerically pure immunologically active carbocyclic nor-muramyldipeptide analogues (1'R,2'R)-/(1'S,2'S)-N-[2-(2'-acetylaminocyclohexyloxy)acetyl]-L- alanyl-D-isoglutamine and (1'R,2'R)-/(1'S,2'S)-N-[2-(2'-acetylaminocyclohexyloxy)acetyl]-L- alanyl-D-glutamic acid is described. The title compounds were synthesized using two independent synthetic routes from racemic trans-2-azidocyclohexanol and (1R,2R)-/(1S,2S)-2-aminocyclohexanol, respectively.