127969-90-8Relevant articles and documents
Synthesis of a series of promising isobenzofuranones for the treatment of acute mucositis caused by chemo- and radiotherapy
Patoor, Maude,Neuner, Philippe,Ruffner, Heinz,Spanka, Carsten,Bouchez, Laure C.
, p. 2397 - 2400 (2013/11/06)
A small series of 3,5-dihydroxy-7-methoxy-3,6-dimethylshyisobenzofuran- 1(3H)-one analogues of the immunosuppressant, mycophenolate mofelite (MMF), has been identified during a screening campaign as possible mediators to prevent mucositis. Herein, we pres
CYCLISATION PROCESS OF FORMING A MULTIPLE RING COMPOUND
-
Page/Page column 53-55, (2010/11/28)
The present invention relates to a cyclisation process of forming a multiple ring compound from an isoprenoid compound. The cyclisation process involves reacting the isoprenoid compound with an acetal initiator under conditions sufficient to form the multiple ring compound. The isoprenoid compound is contacted with an initiator an optionally with a catalyst. Cyclisation occurs by reaction of the initiator with the isoprenoid compound. Cyclic aceta compounds wherein the acetal forms part of 6-membered unsaturated ring are also defined.