1279719-11-7

Basic information

• Product Name: 2-phenyl-3-(phenylsulfonyl)-1H-indole
• Synonyms: 2-phenyl-3-(phenylsulfonyl)-1H-indole
• CAS NO: 1279719-11-7
• Molecular Weight: 333.411
• Mol File: 1279719-11-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-phenyl-3-(phenylsulfonyl)-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenyl-3-(phenylsulfonyl)-1H-indole(1279719-11-7)
• EPA Substance Registry System: 2-phenyl-3-(phenylsulfonyl)-1H-indole(1279719-11-7)

Safety Data

• Hazardous Substances Data: 1279719-11-7(Hazardous Substances Data)

Upstream product

• 1279718-89-6 C₂₀H₁₅N₃O₂S 
• 3112-88-7 Benzyl phenyl sulfone 
• 552-89-6 2-nitro-benzaldehyde 
• 948-65-2 2-phenyl-indole 
• 98-09-9 benzenesulfonyl chloride 
• 618-41-7 Benzenesulfinic acid 
• 199277-23-1 1-azido-2-(phenylethynyl)benzene 
• 1417819-67-0 1-azido-4-methyl-2-(phenylethynyl)benzene 
• 873-55-2 sodium benzenesulfonate 

Relevant articles and documents

Eosin y photoredox catalyzed net redox neutral reaction for regiospecific annulation to 3-sulfonylindoles: Via anion oxidation of sodium sulfinate salts

An eosin Y photoredox catalyzed net redox neutral process for 3-sulfonylindoles via the anionic oxidation of sodium sulfinate salts and its radical cascade cyclization with 2-alkynyl-azidoarenes was developed with visible light as a mediator. The reaction offers metal and oxidant/reductant free, visible light mediated vicinal sulfonamination of alkynes to 2-aryl/alkyl-3-sulfonylindoles and proceeds via the generation of a sulfur-centered radical through direct oxidation of the sulfinate anion by an excited photocatalyst with a reductive quenching cycle. The mild conditions, use of an organic dye as photo-catalyst, bench stability and easily accessible starting materials make the present approach green and attractive.

ZnO-mediated regioselective C-arylsulfonylation of indoles: A facile solvent-free synthesis of 2- and 3-sulfonylindoles and preliminary evaluation of their activity against drug-resistant mutant HIV-1 reverse transcriptases (RTs)

A ZnO-mediated one-pot solvent-free protocol for the regioselective C-arylsulfonylation of indoles is described and some novel derivatives were tested on wild type and non-nucleoside inhibitor resistant K103N and Y181C HIV-1 reverse transcriptases (RTs).