1280203-63-5

Basic information

• Product Name: N-(3,5-di(trifluoromethyl)phenyl)-1-(2,6-dimethylphenyl)-5-oxopyrrolidine-3-carboxamide
• CAS NO: 1280203-63-5
• Molecular Weight: 444.377
• Mol File: 1280203-63-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(3,5-di(trifluoromethyl)phenyl)-1-(2,6-dimethylphenyl)-5-oxopyrrolidine-3-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3,5-di(trifluoromethyl)phenyl)-1-(2,6-dimethylphenyl)-5-oxopyrrolidine-3-carboxamide(1280203-63-5)
• EPA Substance Registry System: N-(3,5-di(trifluoromethyl)phenyl)-1-(2,6-dimethylphenyl)-5-oxopyrrolidine-3-carboxamide(1280203-63-5)

Safety Data

• Hazardous Substances Data: 1280203-63-5(Hazardous Substances Data)

Upstream product

• 328-73-4 3,5-bis(trifluoromethyl)iodobenzene 
• 1449510-53-5 (2,6-dimethylphenyl)(phenyl)iodonium triflate 
• 123084-61-7 (2,6-dimethylphenyl)-λ³-iodanediyl diacetate 

Relevant articles and documents

Sterically Congested 2,6-Disubstituted Anilines from Direct C?N Bond Formation at an Iodine(III) Center

2,6-Disubstituted anilines are readily prepared from the direct reaction between amides and diaryliodonium salts. As demonstrated for 24 different examples, the reaction is of unusually broad scope with respect to the sterically congested arene and the nitrogen source, occurs without the requirement for any additional promoter, and proceeds through a direct reductive elimination at the iodine(III) center. The efficiency of the coupling procedure is further demonstrated within the short synthesis of a chemerin binding inhibitor.