1280497-50-8

Basic information

• Product Name: 5-(4-fluorophenyl)-1-(2-nitrobenzyl)-1H-1,2,3-triazole
• CAS NO: 1280497-50-8
• Molecular Weight: 298.276
• Mol File: 1280497-50-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-(4-fluorophenyl)-1-(2-nitrobenzyl)-1H-1,2,3-triazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-fluorophenyl)-1-(2-nitrobenzyl)-1H-1,2,3-triazole(1280497-50-8)
• EPA Substance Registry System: 5-(4-fluorophenyl)-1-(2-nitrobenzyl)-1H-1,2,3-triazole(1280497-50-8)

Safety Data

• Hazardous Substances Data: 1280497-50-8(Hazardous Substances Data)

Upstream product

• 3958-60-9 2-nitrophenylmethyl bromide 
• 766-98-3 1-ethynyl-4-fluorobenzene 
• 95668-86-3 1-(azidomethyl)-2-nitrobenzene 

Relevant articles and documents

Sequential one-pot ruthenium-catalyzed azide-alkyne cycloaddition from primary alkyl halides and sodium azide

An experimentally simple sequential one-pot RuAAC reaction, affording 1,5-disubstituted 1H-1,2,3-triazoles in good to excellent yields starting from an alkyl halide, sodium azide, and an alkyne, is reported. The organic azide is formed in situ by treating the primary alkyl halide with sodium azide in DMA under microwave heating. Subsequent addition of [RuClCp*(PPh 3)2] and the alkyne yielded the desired cycloaddition product after further microwave irradiation.