128056-99-5

Basic information

• Product Name: (2R,3S)-1,2-O-isopropylidene-3-O-(p-toluenesulfonyl)-1,2,3,4-butanetetrol
• Synonyms: (2R,3S)-1,2-O-isopropylidene-3-O-(p-toluenesulfonyl)-1,2,3,4-butanetetrol
• CAS NO: 128056-99-5
• Molecular Weight: 316.375
• Mol File: 128056-99-5.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (2R,3S)-1,2-O-isopropylidene-3-O-(p-toluenesulfonyl)-1,2,3,4-butanetetrol(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3S)-1,2-O-isopropylidene-3-O-(p-toluenesulfonyl)-1,2,3,4-butanetetrol(128056-99-5)
• EPA Substance Registry System: (2R,3S)-1,2-O-isopropylidene-3-O-(p-toluenesulfonyl)-1,2,3,4-butanetetrol(128056-99-5)

Safety Data

• Hazardous Substances Data: 128056-99-5(Hazardous Substances Data)

Upstream product

• 126946-54-1 ethyl (2R,3R)-3,4-O-isopropylidene-2-p-toluenesulfonyl-3,4-dihydroxybutanoate 
• 98-59-9 p-toluenesulfonyl chloride 
• 126946-53-0 ethyl (2R,3S)-3,4-O-isopropylidene-2-p-toluenesulfonyl-3,4-dihydroxybutanoate 
• 1379602-81-9 (2R)-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl](hydroxy)ethanoic acid sodium salt 
• 15042-01-0 5,6-O-isopropylidene-L-ascorbic acid 
• 92973-40-5 methyl (2R,3S)-3,4-O-isopropylidene-2,3,4-trihydroxybutanoate 
• 166249-17-8 methyl (2R,3S)-3,4-O-isopropylidene-2,3,4-trihydroxy-2-O-(p-toluenesulfonyl)butanoate 
• 92973-39-2 O³,O⁴-(1-methylethylidene)-L-threonic acid 

Downstream Products

• 1418112-79-4 4-chloro-6-((R)-1-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)ethoxy)-2-(4-fluorobenzylthio)pyrimidine 
• 1418112-80-7 N-(6-((R)-1-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)ethoxy)-2-(4-fluorobenzyl-thio)pyrimidin-4-yl)-3-methylazetidine-1-sulfonamide 
• 128111-95-5 (2R,3R)-2-<2-O-benzyl-3,4-O-isopropylidene-2,3,4-trihydroxybut-1-yl>-1,3-dithiane 
• 128057-00-1 (3R,4R)-3-O-benzyl-4,5-O-isopropylidene-3,4,5-trihydroxypentanal 
• 128112-01-6 (2R,3S)-2-<2-O-benzyl-3,4-O-isopropylidene-2,3,4-trihydroxybut-1-yl>-1,3-dithiane 
• 128057-04-5 (3R,4S)-3-O-benzyl-4,5-O-isopropylidene-3,4,5-trihydroxypentanal 
• 74134-79-5 (4R)-2,2-dimethyl-4-[(2R)-oxiran-2-yl]-1,3-dioxolane 
• 74134-78-4 (2S,3R)-3,4-epoxy-1,2-O-isopropylidenebutane-1,2-diol 

Relevant articles and documents

Packaging comprising forms of sodium salt of 4-tert-butyl-N-[4-chloro-2-(1-oxy-pyridine-4-carbonyl)-phenyl]-benzenesulfonamide

The invention relates to a packaging comprising a multitude (A) of at least 2 administration units comprising polymorphic trihydrated forms of sodium salt of 4-tert-butyl-N-[4-chloro-2-(1-oxy-pyridine-4-carbonyl)-phenyl]-benzenesulfonamide; or (B) of at least 2 administration units comprising polymorphic solvated or desolvated forms of sodium salt of 4-tert-butyl-N-[4-chloro-2-(1-oxy-pyridine-4-carbonyl)-phenyl]-benzenesulfonamide.

CRYSTALLINE FORMS OF N-[2-[[(2,3-DIFLUOROPHENYL)METHYL]THIO]-6--4-PYRIMIDINYL]-1-AZETIDINESULFONAMIDE

There is provided crystalline forms of N-[2-[[(2,3-difluorophenyl)methyl]thio]-6-{[(1R,2S)-2,3-dihydroxy-1-methylpropyl]oxy}-4-pyrimidinyl]1-azetidinesulfon-amide anhydrate. Such compounds/forms may be useful in the treatment of a disease/condition in which modulation of chemokine receptor activity is beneficial.

Synthesis of enantiomeric 9-(2′,3′,4′-trihydroxybutyl)adenine derivatives from L-ascorbic and D-isoascorbic acids

L-Ascorbic and D-isoascorbic acids were employed in syntheses of 9-(2′,3′,4′-trihydroxybutyl)adenines protected at 3′ and 4′ oxygens (all four enantiomers) and at 2′ oxygen (2′S,3′R and 2′S,3′S enantiomers).