128097-70-1Relevant articles and documents
2,5-BIS(TRIFLUOROMETHYL)-1,3,4-OXADIAZOLE IN CYCLOADDITION REACTIONS
Vasil'ev, N. V.,Lyashenko, Yu. E.,Galakhov, M. V.,Kolomiets, A. F.,Gontar', A. F.,Sokol'skii, G. A.
, p. 81 - 85 (2007/10/02)
The cycloaddition of 2,5-bis(trifluoromethyl)-1,3,4-oxadiazole to dienophiles with cyclic and acyclic structures takes place according to a two-step mechanism with the extrusion of nitrogen and results in the formation of derivatives of 7-oxabicycloheptanes.A significant influence of the donor properties of the dienophiles, as well as the spatial factors, on the realization of these processes has been discovered.However, solvation effects do not have a significant effect on the formation of the cycloadducts.The regio- and stereoselectivity of the cycloaddition reactions has been noted.