128120-02-5 Usage
Description
CHEMBRDG-BB 4015909, also known as 1-Phenyl-3-pyrrolidinone, is a chemical compound that serves as a reagent in the synthesis of various organic compounds. It is particularly utilized in the preparation of non-classical antifolates and azetidineand pyrrolidine-containing alkynes, which have potential applications in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
CHEMBRDG-BB 4015909 is used as a reagent for the synthesis of non-classical antifolates, which are evaluated for their in vitro cytotoxicity. These antifolates have potential applications in cancer treatment and other therapeutic areas.
Used in Medicinal Chemistry Research:
CHEMBRDG-BB 4015909 is used in the preparation of azetidineand pyrrolidine-containing alkynes, which are mGluR5 regulators. These compounds have potential applications in the treatment of neurological disorders and cognitive enhancement.
Used in Chemical Synthesis:
CHEMBRDG-BB 4015909 is used as a building block in the synthesis of various organic compounds, contributing to the development of new pharmaceuticals, agrochemicals, and other specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 128120-02-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,8,1,2 and 0 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 128120-02:
(8*1)+(7*2)+(6*8)+(5*1)+(4*2)+(3*0)+(2*0)+(1*2)=85
85 % 10 = 5
So 128120-02-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H11NO/c12-10-6-7-11(8-10)9-4-2-1-3-5-9/h1-5H,6-8H2
128120-02-5Relevant articles and documents
MGLUR REGULATORS
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Page/Page column 100; 101; 102, (2014/09/03)
Provided herein are compounds of the formula I: (I), as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment or prevention of mGluR5 mediated disorders, such as acute and/or chronic neurological disorders, cognitive disorders and memory deficits, as well as acute and chronic pain.
6,7-dihydropyrrol[3,4-c]pyrido[2,3-d]pyrimidine derivatives
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, (2008/06/13)
The present invention concerns compounds of the formula: STR1 wherein R is a lower alkyl group, an aryl group or an alkylaryl group and X and Y are the same or different, and each is OH, NH2, or SH. The aryl group or the aryl moiety of the alkylaryl group may be unsubstituted, monosubstituted, disubstituted or trisubstituted. If substituted, each substituent may independently be an alkyl group, an alkyloxy group or a halogen. The present invention also provides methods for synthesizing the compounds described above.