128203-42-9

Basic information

• Product Name: 2H-1,3-Benzoxazine, 6,8-bis(1,1-dimethylethyl)-3,4-dihydro-3-methyl-
• CAS NO: 128203-42-9
• Molecular Formula: C17H27NO
• Molecular Weight: 261.407
• Mol File: 128203-42-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2H-1,3-Benzoxazine, 6,8-bis(1,1-dimethylethyl)-3,4-dihydro-3-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-1,3-Benzoxazine, 6,8-bis(1,1-dimethylethyl)-3,4-dihydro-3-methyl-(128203-42-9)
• EPA Substance Registry System: 2H-1,3-Benzoxazine, 6,8-bis(1,1-dimethylethyl)-3,4-dihydro-3-methyl-(128203-42-9)

Safety Data

• Hazardous Substances Data: 128203-42-9(Hazardous Substances Data)

Upstream product

• 128203-38-3 2,4-Di-tert-butyl-6-phenol 
• 120695-70-7 Methylimino-2,2'-dimethylene-bis-(4,6-di-tert-butyl-phenol) 
• 96-76-4 2,4-di-tert-Butylphenol 
• 100-97-0 hexamethylenetetramine 
• 128203-39-4 N,N-Dimethyl-(3,5-di-tert-butyl-2-hydroxyphenyl)-methylamine-oxide 
• 32857-07-1 2,4-di-tert-butyl-6-(1,1-dimethylaminomethyl)phenol 

Downstream Products

• 3383-21-9 3,5-di-tert-butyl-o-benzoquinone 
• 37942-07-7 3,5-di-tert-butyl-2-hydroxybenzaldehyde 

Relevant articles and documents

New opportunities for duff reaction

Reaction of 2,4-di-tert-butylphenol with urotropin in conditions of Duff reaction takes an abnormal route and instead of the expected di-tert-butylsalicylaldehyde provides a mixture of N-substituted 3,5-di-tert-butyl-2-hydroxybenzylamines and redox conjugate benzoxazines containing mostly 6,8-di-tert-butyl-3-(3,5-di-tert-butyl-2-hydroxybenzyl)-2H-3, 4-dihydrobenz[e][1,3]oxazine. A solvolysis of an individual benzoxazine in the system HO(CH2)2OH-H2O-HCl affords di(3,5-di-tert-butyl-2-hydroxybenzyl)amine, and in AcOH 3,5-di-tert- butylsalicilaldehyde. A mechanism of Duff reaction was suggested involving the formation of a benzoxazine intermediate. 2005 Pleiades Publishing, Inc.

SEMI-HINDERED PHENOLS. 1. SYNTHESIS OF 3,5-DI-TERT-BUTYLSALICYLIC ALDEHYDE

Some differences were observed in the solid- and liquid-phase benzylic oxidation of 2-(hydroxy- or dialkylamino)methyl-4,6-di-tert-butylphenols.Oxidation of these semi-hindered phenols with lead tetraacetate gave a new compound: 3,5-di-tert-butyl-ortho-benzoquinone diacylal.Keywords: semi-hindered phenols, synthesis, aldehyde, benzylic alcohol, oxidation, liquid phase, solid phase.