1282034-12-1

Basic information

• Product Name: N-butyl-N-methyl-4-(trifluoromethyl)benzenamine
• Synonyms: N-butyl-N-methyl-4-(trifluoromethyl)benzenamine
• CAS NO: 1282034-12-1
• Molecular Weight: 231.261
• Mol File: 1282034-12-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: N-butyl-N-methyl-4-(trifluoromethyl)benzenamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-butyl-N-methyl-4-(trifluoromethyl)benzenamine(1282034-12-1)
• EPA Substance Registry System: N-butyl-N-methyl-4-(trifluoromethyl)benzenamine(1282034-12-1)

Safety Data

• Hazardous Substances Data: 1282034-12-1(Hazardous Substances Data)

Upstream product

• 1028330-26-8 N-butyl-N-methyl isonicotinamide 
• 98-56-6 4-chlorobenzotrifluoride 
• 1117-72-2 N-methyl-N-n-butylformamide 
• 110-68-9 N-n-butyl-N-methylamine 
• 1263276-85-2 N,N-dimethyl-4-(trifluoromethyl)benzene-1-sulfonamide 
• 402-44-8 4-Fluorobenzotrifluoride 
• 34857-71-1 4-trifluoromethylphenyl N,N-diethylcarbamate 
• 1201594-37-7 (4-[trifluoromethyl]phenyl) N,N-dimethylsulfamate 

Relevant articles and documents

Nickel-Catalyzed Amination of Aryl Chlorides with Amides

A nickel-catalyzed amination of aryl chlorides with diverse amides via C-N bond cleavage has been realized under mild conditions. A broad substrate scope with excellent functional group tolerance at a low catalyst loading makes the protocol powerful for synthesizing various aromatic amines. The aryl chlorides could selectively couple to the amino fragments rather than the carbonyl moieties of amides. Our protocol complements the conventional amination of aryl chlorides and expands the usage of inactive amides.

Nickel-catalyzed coupling of fluoroarenes and amines

The combination of bis(cyclooctadiene)nickel [Ni(COD)2] and 1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene hydrochloride (IPr×HCl) effectively catalyzes coupling of fluoroarenes with amines in the presence of sodium tert-butoxide (t-BuONa). A

Nickel-catalyzed amination of aryl sulfamates and carbamates using an air-stable precatalyst

A facile nickel-catalyzed method to achieve the amination of synthetically useful aryl sulfamates and carbamates is reported. Contrary to most Ni-catalyzed amination reactions, this user-friendly approach relies on an air-stable Ni(II) precatalyst, which, when employed with a mild reducing agent, efficiently delivers aminated products in good to excellent yields. The scope of the method is broad with respect to both coupling partners and includes heterocyclic substrates.