128304-84-7 Usage
Description
3-(N-BOC-METHYLAMINO)PROPIONITRILE is a chemical compound with the molecular formula C9H16N2O2. It is a derivative of propionitrile with a BOC-protected methylamino group attached to the third carbon. The BOC (tert-butoxycarbonyl) group serves as a protective group for the amino function, preventing unwanted reactions and allowing for selective deprotection.
Uses
Used in Pharmaceutical Industry:
3-(N-BOC-METHYLAMINO)PROPIONITRILE is used as a building block in organic synthesis for the preparation of pharmaceuticals. It is a versatile intermediate that can undergo various transformations to introduce different functional groups, making it useful in the development of new chemical entities.
Used in Agrochemical Industry:
3-(N-BOC-METHYLAMINO)PROPIONITRILE is used as a building block in organic synthesis for the preparation of agrochemicals. Its versatility allows for the development of new chemical entities for agricultural applications.
Used in Research and Development:
3-(N-BOC-METHYLAMINO)PROPIONITRILE can serve as a substrate for the development of new catalytic reactions and synthetic methodologies, contributing to advancements in the field of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 128304-84-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,8,3,0 and 4 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 128304-84:
(8*1)+(7*2)+(6*8)+(5*3)+(4*0)+(3*4)+(2*8)+(1*4)=117
117 % 10 = 7
So 128304-84-7 is a valid CAS Registry Number.
128304-84-7Relevant articles and documents
Privileged 1,2,4-oxadiazoles in anticancer drug design: Novel 5-aryloxymethyl-1,2,4-oxadiazole leads for prostate cancer therapy
Lukin, Alexey,Karapetian, Ruben,Ivanenkov, Yan,Krasavin, Mikhail
, p. 198 - 204 (2016/03/15)
Based on the structure of the previously identified leads, new series of compounds containing 1,2,4-oxadiazole core was designed. A small, diverse library of 51 compounds including both 2-(acylamino)ethyl and 2-ureidoethyl side chains was synthesized using parallel chemistry and tested for antiproliferative activity against prostate cancer DU-145 cell line. Four hit compounds - all belonging to 2-ureidoethyl series - were identified and three compounds were confirmed as 10-20 μM inhibitors. The similarity in compounds' periphery and the data obtained previously suggest a similar mode of action for these compounds which was postulated as tubulin inhibition and was confirmed by in silico docking. These data provide further evidence for the privileged character of 1,2,4-oxadiazoles in antiproliferative compound design.
TETRAHYDROQUINOLINE DERIVATIVES AND THEIR PHARMACEUTICAL USE
-
Page/Page column 76, (2011/06/11)
Tetrahydroquinoline compounds of Formula (I) and salts thereof, pharmaceutical compositions containing such compounds and their use in therapy.
