1283073-92-6Relevant articles and documents
Rhodium(iii)-catalyzed regioselective oxidative annulation of anilines and allylbenzenes: Via C(sp3)-H/C(sp2)-H bond cleavage
Liu, Yunqi,Yang, Yudong,Wang, Chunxia,Wang, Zhishuo,You, Jingsong
, p. 1068 - 1071 (2019)
Described herein is the merging of allylic C(sp3)-H activation and directed C(sp2)-H activation into a single approach for discovering unprecedented chemical transformations. As a proof-of-concept, we disclose for the first time the
Ruthenium-catalyzed heteroatom-directed regioselective C-H arylation of indoles using a removable tether
Tiwari, Virendra Kumar,Kamal, Neha,Kapur, Manmohan
, p. 1766 - 1769 (2015/04/14)
A new approach to C-2 arylated indoles has been developed by utilizing a ruthenium-catalyzed, heteroatom-directed regioselective C-H arylation. The reaction is highly site-selective and results in very good yields. The highlight of the work is the use of a removable directing group and compatibility of the catalytic system with halogen functional groups in the substrates.
Synthesis of N-(2-pyridyl)indoles via Pd(II)-catalyzed oxidative coupling
Chen, Jinlei,Pang, Qingyu,Sun, Yanbo,Li, Xingwei
, p. 3523 - 3526 (2011/06/24)
Readily available Pd(II) chloride catalysts can catalyze selective and efficient oxidative coupling between N-aryl-2-aminopyridines and internal alkynes to yield N-(2-pyridyl)indoles. This process involves the ortho C-H activation of N-aryl-2-aminopyridines, and CuCl2 was used as an oxidant. Compared to our previously reported Rh(III)-catalyzed synthesis of this class of product, this method is advantageous with a wider scope of alkynes and cost-effective Pd(II) catalysts. Molecular oxygen can be used as a terminal oxidant.
