1283727-48-9

Basic information

• Product Name: 1-[2-chloro-2-(4-fluorophenyl)ethyl]-N-(pyridin-4-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
• Synonyms: 1-[2-chloro-2-(4-fluorophenyl)ethyl]-N-(pyridin-4-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
• CAS NO: 1283727-48-9
• Molecular Weight: 382.828
• Mol File: 1283727-48-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-[2-chloro-2-(4-fluorophenyl)ethyl]-N-(pyridin-4-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[2-chloro-2-(4-fluorophenyl)ethyl]-N-(pyridin-4-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine(1283727-48-9)
• EPA Substance Registry System: 1-[2-chloro-2-(4-fluorophenyl)ethyl]-N-(pyridin-4-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine(1283727-48-9)

Safety Data

• Hazardous Substances Data: 1283727-48-9(Hazardous Substances Data)

Upstream product

• 1451010-32-4 2-(4-chloro-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-1-(4-fluorophenyl)ethanol 
• 1451010-29-9 2-(4-chloro-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-1-(4-fluorophenyl)ethanone 
• 5399-92-8 4-chloro-1H-pyrazolo[3,4-d]pyrimidine 
• 3731-53-1 4-(aminomethyl)pyridine 
• 1013930-73-8 4-chloro-1-[2-chloro-2-(4-fluorophenyl)ethyl]-1H-pyrazolo[3,4-d]-pyrimidine 

Relevant articles and documents

An alternative synthetic approach for the synthesis of biologically relevant 1,4-disubstituted pyrazolo[3,4-d]pyrimidines

A versatile approach for the synthesis of 1,4-disubstituted pyrazolo[3,4-d]pyrimidines has been developed. Starting from commercially available allopurinol, TBAF mediated N1-functionalization and subsequent C4 nucleophilic substitution, under microwave assisted- or standard heating conditions, granted access to highly functionalized pyrazolo[3,4-d]pyrimidines of potential biological interest.