128387-05-3

Basic information

• Product Name: Triacetyl-cis-threo-Dl-sphingosin
• CAS NO: 128387-05-3
• Molecular Weight: 425.609
• Mol File: 128387-05-3.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Triacetyl-cis-threo-Dl-sphingosin(CAS DataBase Reference)
• NIST Chemistry Reference: Triacetyl-cis-threo-Dl-sphingosin(128387-05-3)
• EPA Substance Registry System: Triacetyl-cis-threo-Dl-sphingosin(128387-05-3)

Safety Data

• Hazardous Substances Data: 128387-05-3(Hazardous Substances Data)

Upstream product

• 123-78-4 D,L-Sphingosin 
• 108-24-7 acetic anhydride 
• 143517-04-8 N-[(1R,2S)-3-[(4-Methoxy-phenyl)-diphenyl-methoxy]-2-(2-trimethylsilanyl-ethoxymethoxy)-1-(2-trimethylsilanyl-ethoxymethoxymethyl)-propyl]-acetamide 
• 128308-05-4 N-[(E)-(1R,2R)-2-(2-Trimethylsilanyl-ethoxymethoxy)-1-(2-trimethylsilanyl-ethoxymethoxymethyl)-heptadec-3-enyl]-acetamide 
• 143517-05-9 N-[(1R,2S)-3-Oxo-2-(2-trimethylsilanyl-ethoxymethoxy)-1-(2-trimethylsilanyl-ethoxymethoxymethyl)-propyl]-acetamide 
• 128308-04-3 N-[(1R,2S)-3-Hydroxy-2-(2-trimethylsilanyl-ethoxymethoxy)-1-(2-trimethylsilanyl-ethoxymethoxymethyl)-propyl]-acetamide 
• 25791-20-2 (n-tetradecyl)triphenylphosphonium bromide 
• 231291-97-7 (E)-(2R,3R)-2-(4-Methoxy-benzylamino)-octadec-4-ene-1,3-diol 
• 124-25-4 myristylaldehyde 
• 787632-41-1 N-[(1R,2S,3S)-3-Hydroxy-2-(4-methoxy-benzyloxy)-1-(4-methoxy-phenoxymethyl)-pent-4-enyl]-acetamide 
• 787632-42-2 (4R,5S,6R)-5-(4-Methoxy-benzyloxy)-4-(4-methoxy-phenoxymethyl)-2-methyl-6-vinyl-5,6-dihydro-4H-[1,3]oxazine 
• 787632-44-4 (4R,5S,6S)-5-(4-Methoxy-benzyloxy)-4-(4-methoxy-phenoxymethyl)-2-methyl-6-vinyl-5,6-dihydro-4H-[1,3]oxazine 
• 15890-72-9 laurylmagnesium bromide 
• 934487-04-4 5-(4-methoxy-benzyloxy)-4-(4-methoxy-phenoxymethyl)-2-methyl-6-vinyl-5,6-dihydro-4H-[1,3]oxazine 

Downstream Products

• 3102-57-6 N-((1RS,2SR)-2-hydroxy-1-hydroxymethyl-heptadec-3c-enyl)-acetamide 
• 81819-46-7 N-[(2R,4S,5R)-4-((E)-Pentadec-1-enyl)-2-phenyl-[1,3]dioxan-5-yl]-acetamide 

Relevant articles and documents

Stereoselective synthesis of trans-olefins by the copper-mediated SN2′ reaction of vinyl oxazines with Grignard reagents. Asymmetric synthesis of d-threo-sphingosines

The SN2′ reaction of 6-vinyl-5,6-dihydro-4H-[1,3]oxazines with Grignard reagents in the presence of CuCN was studied, and high trans selectivity for the formation of double bond was observed with a variety of RMgX. The SN2′ reaction,

Enantiopure aminotriol from D-isoascorbic acid synthesis of D-threo-C-18-sphingosine

Enantiopure suitably N,O-protected aminotriol has been prepared from D-isoascorbic acid. The utility of this homochiral building block in the synthesis of (2R,3R)-D-threo-C18-sphingosine is described via a Wittig reaction on a N,O-protected β-a

Synthesis of two pairs of enantiomeric C18-sphingosines

Two pairs of enantiomeric (D-erythro, L-erythro, D-threo, L-threo) C18-sphingosines have been synthesized from Z-butene-1,4-diol utilizing Sharpless asymmetric epoxidation and a regiospecific ring-opening reaction of the resulting C4-chiral epoxide with an azide anion.