128396-36-1

Basic information

• Product Name: Quinoline, 2-(1E)-1-pentenyl-
• CAS NO: 128396-36-1
• Molecular Formula: C14H15N
• Mol File: 128396-36-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Quinoline, 2-(1E)-1-pentenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Quinoline, 2-(1E)-1-pentenyl-(128396-36-1)
• EPA Substance Registry System: Quinoline, 2-(1E)-1-pentenyl-(128396-36-1)

Safety Data

• Hazardous Substances Data: 128396-36-1(Hazardous Substances Data)

Upstream product

• 91-63-4 2-methylquinoline 
• 71-36-3 butan-1-ol 
• 5470-96-2 quinoline 2-carbaldehyde 
• 1779-51-7 n-butyl(triphenyl)phosphonium bromide 
• 4491-33-2 ethyl quinoline-2-carboxylate 
• 93-10-7 quinoline-2-carboxylic acid 
• 109-73-9 N-butylamine 
• 123-72-8 butyraldehyde 

Relevant articles and documents

Synthesis and biological evaluation of substituted quinolines: Potential treatment of protozoal and retroviral co-infections

We report the synthesis of substituted quinolines and their in vitro biological evaluation against the causal agents of cutaneous leishmaniasis, visceral leishmaniasis, African trypanosomiasis and Chagas' disease. Furthermore, several quinolines have also been tested for their anti-retroviral activity in HIV-1 infected cells. The structure-activity relationships of these new synthetic compounds are discussed and emphasis was placed on the treatment of leishmania/HIV co-infections.

Manganese-Catalyzed Direct Olefination of Methyl-Substituted Heteroarenes with Primary Alcohols

Herein, we present the first catalytic direct olefination of methyl-substituted heteroarenes with primary alcohols through an acceptorless dehydrogenative coupling. The reaction is catalyzed by a complex of the earth-abundant transition metal manganese that is stabilized by a bench-stable NNN pincer ligand derived from 2-hydrazinylpyridine. The reaction is environmentally benign, producing only hydrogen and water as byproducts. A large number of E-disubstituted olefins were selectively obtained with high efficiency.

Lanthanum Pentafluorobenzoate-Catalyzed Aerobic Oxidative Olefination of Benzylamines with 2-Methylquinoline through Deamination and C-H Bond Functionalization

An efficient direct aerobic oxidative olefination of the methyl groups of 2-methylquinolines with benzylamines in the presence of a rare-earth-metal Lewis acid catalyst to give 2-styrylquinolines was successfully developed. Preliminary mechanistic studies revealed that the oxidative olefination reaction proceeds through a Lewis acid-catalyzed 2-methylquinoline-aldehyde condensation and an amine-aldehyde condensation.