128400-42-0

Basic information

• Product Name: S-[2-(4-fluorophenyl)-2-oxoethyl]-O-ethyl dithiocarbonate
• Synonyms: S-[2-(4-fluorophenyl)-2-oxoethyl]-O-ethyl dithiocarbonate
• CAS NO: 128400-42-0
• Molecular Weight: 258.338
• Mol File: 128400-42-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: S-[2-(4-fluorophenyl)-2-oxoethyl]-O-ethyl dithiocarbonate(CAS DataBase Reference)
• NIST Chemistry Reference: S-[2-(4-fluorophenyl)-2-oxoethyl]-O-ethyl dithiocarbonate(128400-42-0)
• EPA Substance Registry System: S-[2-(4-fluorophenyl)-2-oxoethyl]-O-ethyl dithiocarbonate(128400-42-0)

Safety Data

• Hazardous Substances Data: 128400-42-0(Hazardous Substances Data)

Upstream product

• 140-89-6 potassium ethyl xanthogenate 
• 140-90-9 sodium O-ethyl dithiocarbonate 
• 403-29-2 2-bromo-4'-fluoroacetophenone 
• 3488-44-6 1-(4-fluorophenyl)-2-diazoethan-1-one 

Downstream Products

• 517867-11-7 1-ethoxythiocarbonylsulfanyl-4-(4-fluorophenyl)-4-oxobutyl 2,2-dimethylpropionate 
• 1101207-11-7 tert-butyl 2-(7-fluoro-4-oxo-1,2,3,4-tetrahydronaphthalen-1-yl)ethoxycarbamate 
• 1101207-10-6 tert-butyl 3-(ethoxycarbonothioylthio)-6-(4-fluorophenyl)-6-oxohexyloxycarbamate 
• 1164111-67-4 (E)-4-(4-chloro-phenyl)-7-(4-fluoro-phenyl)-7-oxo-hept-2-enoic acid ethyl ester 
• 58861-48-6 2-(4-fluorophenyl)thiophene 
• 1509927-78-9 4-[3-(4-fluorophenyl)-3-oxopropyl][1,3]dithietan-2-one 
• 1608082-66-1 S-1-(N-(4-acetamido-3,5,6-trifluoropyridin-2-yl)acetamido)-5-(4-fluorophenyl)-5-oxopentan-2-yl O-ethyl carbonodithioate 

Relevant articles and documents

Synthesis of pyrazolylvinyl ketones from furan derivatives

A new protocol for the synthesis of pyrazol-5-ylvinyl ketones, e.g. pyrazole-chalcones, employing furfuryl ketones as a triketone equivalent, has been developed. The reaction occurs under mild conditions and does not require the use of expensive materials

Electrochemical reactivity of S-phenacyl-O-ethyl-xanthates in hydroalcoholic (MeOH/H2O 4:1) and anhydrous acetonitrile media

The electrochemical behavior of a series of S-phenacyl-O-ethyl-xanthates (O-ethyl-dithiocarbonate acetophenone derivatives) in hydroalcoholic (MeOH/H2O 4:1) and anhydrous media (ACN/TBAPF6) using carbon electrodes was studied. Cyclic voltammetry showed in hydroalcoholic media only two cathodic waves, whereas in ACN one anodic and two cathodic waves were present. The first cathodic wave corresponded to the reduction of the phenylketone group, whereas the first anodic was attributed to the xanthate unit. Macroelectrolysis on graphite and vitreous carbon at anodic and cathodic potentials, let us to explore the synthetic potential of this electrochemical reactions. With some compounds in hydroalcoholic media and using carbon electrodes, polymeric material was deposited on the electrode impeding the reaction; this deposit was characterized by AFM and SEM-EDS. The electroreduction on Ti electrode overcome this problem and gave the corresponding acetophenones (>95%). On the other hand, in ACN, small quantities of the dimeric 1,4-dicarbonyl compounds X-PhCOCH2CH2COPh-X (7–15%), as well as the corresponding acetophenones (ca. 50%) were isolated. Oxidation macroelectrolysis showed a very complicated transformation without synthetic value. The reaction mechanism for the reduction and the homolytic dissociation into the phenacyl radical was supported by DFT calculations.

Method of preparing benzazepines and derivatives thereof

The invention relates to a method of preparing benzazepine compounds having general formula (IA) consisting in reacting at least one compound having general formula (IIA) with an olefin, the compound thus obtained then being cyclised such as to produce tetralone, followed by the oxime derivative of same, which, by transformation by a Beckmann rearrangement, gives rise to the desired compounds.