128412-94-2

Basic information

• Product Name: 1,3-Dichloro-2-[(E)-2-(2,6-difluoro-phenyl)-vinyl]-5-methoxy-benzene
• CAS NO: 128412-94-2
• Molecular Weight: 315.147
• Mol File: 128412-94-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,3-Dichloro-2-[(E)-2-(2,6-difluoro-phenyl)-vinyl]-5-methoxy-benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dichloro-2-[(E)-2-(2,6-difluoro-phenyl)-vinyl]-5-methoxy-benzene(128412-94-2)
• EPA Substance Registry System: 1,3-Dichloro-2-[(E)-2-(2,6-difluoro-phenyl)-vinyl]-5-methoxy-benzene(128412-94-2)

Safety Data

• Hazardous Substances Data: 128412-94-2(Hazardous Substances Data)

Upstream product

• 82772-93-8 2,6-dichloro-4-methoxy-benzaldehyde 

Downstream Products

• 128412-74-8 3,5-Dichloro-4-[1,2-diamino-2-(2,6-difluoro-phenyl)-ethyl]-phenol 
• 128412-74-8 3,5-Dichloro-4-[1,2-diamino-2-(2,6-difluoro-phenyl)-ethyl]-phenol 

Relevant articles and documents

Aqua(sulfato)platinum(II) Complexes with Variable Substituents in the 2-Phenyl Ring. 1. Synthesis and Antitumor and Estrogenic Properties

Erythro- and threo-configurated aqua(sulfato)platinum(II) complexes with variable substituents in the 2-phenyl ring (2-PtSO4 to 9-PtSO4: H, 4-F, 3-OH, 4-OH, 2,6-F2, 2,6-Cl2, 2-F/4-OH, 2-Cl/4-OH) were synthesized and tested for estrogenic and antitumor activities.The ligands were obtained by a three-step reaction.The stilbenes were reacted with a mixture of IN3 and NaN3 to yield the respective 1,2-diazido-1,2-diphenylethanes.The subsequent reduction with LiAlH4 led to the corresponding 1,2-diphenylethylenediamines.The (sulfato)platinum(II) complexes were synthesized by reaction of Ag2SO4 with the diiodo complexes, which had been obtained by coordination of the diamines with K2PtI4.Two complexes, erythro-8-PtSO4 and erythro-9-PtSO4, possess antitumor and estrogenic effects and are therefore of interest for the therapy of breast cancer.