128472-98-0Relevant articles and documents
Inhibition of Human Leukocyte Elastase. 2. Inhibition by Substituted Cephalosporin Esters and Amides
Finke, Paul E.,Ashe, Bonnie M.,Knight, Wilson B.,Maycock, Alan L.,Navia, Manuel A.,et al.
, p. 2522 - 2528 (2007/10/02)
A variety of 7α-methoxycephalosporin ester and amide sulfones were prepared and tested to determine the structure-activity relations for inhibition of human leukocyte elastase (HLE), a serine protease which has been implicated in several degenerative lung