128488-62-0

Basic information

• Product Name: Oxazole, 5-phenyl-2-propyl-
• CAS NO: 128488-62-0
• Molecular Formula: C12H13NO
• Molecular Weight: 187.241
• Mol File: 128488-62-0.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: Oxazole, 5-phenyl-2-propyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Oxazole, 5-phenyl-2-propyl-(128488-62-0)
• EPA Substance Registry System: Oxazole, 5-phenyl-2-propyl-(128488-62-0)

Safety Data

• Hazardous Substances Data: 128488-62-0(Hazardous Substances Data)

Upstream product

• 3969-09-3 2-methyl-5-phenyl-1,3-oxazole 
• 75-03-6 ethyl iodide 
• 109-74-0 propyl cyanide 
• 98-86-2 acetophenone 
• 109-73-9 N-butylamine 
• 70-11-1 α-bromoacetophenone 
• 110-69-0 butyraldehyde oxime 
• 536-74-3 phenylacetylene 
• 760-78-1 2-aminopentanoic acid 
• 541-35-5 butanamide 
• 6607-46-1 (1,2-dibromovinyl)benzene 

Relevant articles and documents

CO2/Photoredox-Cocatalyzed Tandem Oxidative Cyclization of α-Bromo Ketones and Amines to Construct Substituted Oxazoles

CO2/photoredox-cocatalyzed tandem oxidative cyclization of α-bromo ketones and amines for the preparation of substituted oxazoles has been achieved. The avoidance of using both transition-metal catalysts and peroxides makes this method more sustainable and renewable.

Metal-Free sp3 C-H Functionalization: PABS/I2-Promoted Synthesis of Polysubstituted Oxazole Derivatives from Arylethanones and 2-Amino-2-alkyl/arylacetic Acid

A nonmetal-catalyzed process for the synthesis of polysubstituted oxazoles from inexpensive and readily available α-amino acids and methyl ketones is established. This reaction is proposed to achieve oxidative cleavage of C(sp3)-H bonds, followed by decarboxylation and annulation. The mild reaction conditions employed in both cases enable the tolerance of a wide range of functional groups as well as high reaction efficiency.

Convenient one-pot synthesis of 2,5-disubstituted oxazoles via a catalytic oxidative dehydrogenation of F3CSO3H·SiO 2-DDQ/CuCl2/LiCl

A facile one-pot synthesis of 2,5-disubstituted oxazoles was developed via cyclization of aldoximes and phenylacetylene then dehydrogenation oxidation. 2,3-dichloro-5,6-dicyano-1,4-benzoquinone was studied for the selective oxidation of oxazolines using Cu2+/Li+ as catalyst and O2 as indirect oxidant. The reaction results showed that this catalyst system can effectively catalyze the oxidation of oxazolines to the corresponding oxazoles. Thus, a variety of polysubstituted oxazoles was easily synthesized in high yields by catalytic oxidation of 2,3-dichloro-5,6-dicyano-1, 4-benzoquinone/CuCl2/LiCl/O2.