128566-93-8

Basic information

• Product Name: Ethyl 2-bromo-4-nitrobenzoate
• Synonyms: Ethyl 2-bromo-4-nitrobenzoate
• CAS NO: 128566-93-8
• Molecular Formula: C₉H₈BrNO₄
• Molecular Weight: 274.06812
• Mol File: 128566-93-8.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 350.8°C at 760 mmHg
• Flash Point: 166°C
• Appearance: /
• Density: 1.594g/cm³
• Vapor Pressure: 4.29E-05mmHg at 25°C
• Refractive Index: 1.576
• CAS DataBase Reference: Ethyl 2-bromo-4-nitrobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 2-bromo-4-nitrobenzoate(128566-93-8)
• EPA Substance Registry System: Ethyl 2-bromo-4-nitrobenzoate(128566-93-8)

Safety Data

• Hazardous Substances Data: 128566-93-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H8BrNO4/c1-2-15-9(12)7-4-3-6(11(13)14)5-8(7)10/h3-5H,2H2,1H3

Upstream product

• 64-17-5 ethanol 
• 16426-64-5 2-bromo-4-nitrobenzoic acid 
• 7745-93-9 2-bromo-4-nitrotoluene 

Downstream Products

• 959778-16-6 4-nitro-2-vinylbenzoic acid ethyl ester 
• 109098-70-6 ethyl-2-bromo-4-amino-benzoate 

Relevant articles and documents

2,3-DIHYDROQUINAZOLIN COMPOUNDS AS NAV1.8 INHIBITORS

The present invention relates to Nav1.8 Inhibitor 2,3-dihydroquinazolin compounds of Formula (X); wherein Y', X', B', R1', R2', R3', R5', R6', R7', and z1 are as defined herein; or pharmaceutically acceptable salts or tautomer forms thereof, corresponding pharmaceutical compositions or formulations, methods or processes of compound preparation, methods, compounds for use in, uses for and/or combination therapies for treating pain and/or pain-related or associated disease(s), disorder(s) or condition(s), respectively.

Impact of electronic modification of the chelating benzylidene ligand in cis-dichloro-configured second-generation olefin metathesis catalysts on their activity

A series of electronically modified second-generation cis-dichloro ruthenium ester chelating benzylidene complexes was prepared, characterized, and benchmarked in a typical ring-opening metathesis polymerization (ROMP) experiment. The electronic tuning of the parent chelating benzylidene ligand (2-ethyl ester benzylidene) was achieved by substitution at the 4- and 5-positions with electron-withdrawing nitro or electron-donating methoxy groups. The effect of the electronic tuning on the cis-trans isomerization process was studied experimentally and theoretically. Density functional theory calculations clearly revealed the influence of electronic modification on the relative stability between the cis and trans isomers, which is decisive for the activity of the studied compounds as initiators in ROMP.

Benzamidoaldehydes and their use as cysteine protease inhibitors

Compounds of the formula where R1, R2, R3, X and n are as defined in the description, are inhibitors of cysteine protease.