128592-58-5

Basic information

• Product Name: (S)-1-Benzo[1,3]dioxol-5-yl-2-[(S)-1-(2,6-dichloro-phenyl)-ethyl]-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline
• CAS NO: 128592-58-5
• Molecular Weight: 486.395
• Mol File: 128592-58-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-1-Benzo[1,3]dioxol-5-yl-2-[(S)-1-(2,6-dichloro-phenyl)-ethyl]-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-Benzo[1,3]dioxol-5-yl-2-[(S)-1-(2,6-dichloro-phenyl)-ethyl]-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline(128592-58-5)
• EPA Substance Registry System: (S)-1-Benzo[1,3]dioxol-5-yl-2-[(S)-1-(2,6-dichloro-phenyl)-ethyl]-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline(128592-58-5)

Safety Data

• Hazardous Substances Data: 128592-58-5(Hazardous Substances Data)

Upstream product

• 2635-13-4 1,2-(methylenedioxy)-4-bromobenzene 
• 128592-47-2 N-[(S)-1-(2,6-Dichloro-phenyl)-ethyl]-N-[2-(3,4-dimethoxy-phenyl)-ethyl]-formamide 
• 121443-83-2 (S)-N-<2-(3,4-Dimethoxyphenyl)ethyl>-1-(2,6-dichlorophenyl)ethylamine 

Relevant articles and documents

Diastereoselective addition of organometallic reagents to chiral iminium ions: Synthesis of (S)-(+)-cryptostyline I

Iminium ion 2c participates in stereoselective nucleophilic addition reactions with Grignard reagents. Analysis of the products from reaction of 5-hexenylmagnesium bromide with iminium ion 2a suggests that these reactions proceed by a polar (two electron) mechanism. The utility of this chemistry is demonstrated in a stereo specific synthesis of (5)-(+)-cryptostylina I.