128649-14-9Relevant articles and documents
OXIDATION OF ALDEHYDES TO α,β-UNSATURATED ALDEHYDES VIA α-CHLOROALDIMINES
Kimpe, Norbert De,Stevens, Christian
, p. 41 - 46 (2007/10/02)
The oxidation of aldehydes to α,β-unsaturated aldehydes has been performed by a sequence of reactions involving conversion into aldimines, chlorination at the α-position to form α-chloroaldimines, base-induced dehydrochlorination and hydrolysis.The four-step transformation can be executed without isolation of the intermediates.This method has been applied to the synthesis of an artificial flavor, i.e. 2-butyl-3-phenylpropenal.