128651-80-9

Basic information

• Product Name: N-(2-Bromobenzylidene)cyclohexylamine
• Synonyms: N-(2-Bromobenzylidene)cyclohexylamine
• CAS NO: 128651-80-9
• Molecular Weight: 266.181
• Mol File: 128651-80-9.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: N-(2-Bromobenzylidene)cyclohexylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-Bromobenzylidene)cyclohexylamine(128651-80-9)
• EPA Substance Registry System: N-(2-Bromobenzylidene)cyclohexylamine(128651-80-9)

Safety Data

• Hazardous Substances Data: 128651-80-9(Hazardous Substances Data)

Upstream product

• 18982-54-2 o-bromobenzyl alcohol 
• 108-91-8 cyclohexylamine 
• 6630-33-7 ortho-bromobenzaldehyde 

Downstream Products

• 1610368-52-9 2-cyclohexyl-2H-indazole 
• 108-91-8 cyclohexylamine 
• 356531-41-4 N-(2-bromobenzyl)cyclohexanamine 
• 514205-41-5 [Pd(C₆H₄C(H)N(C₆H₁₁))Br]2 
• 514205-43-7 [Pd(2-BrC₆H₃C(H)=NC₆H₁₁)(O₂CMe)]2 
• 195-64-2 3,4-(methylenedioxy)phenanthrene 

Relevant articles and documents

Oxidative cross-dehydrogenative coupling (CDC)viaC(sp2)-H bond functionalization:tert-butyl peroxybenzoate (TBPB)-promoted regioselective direct C-3 acylation/benzoylation of 2H-indazoles with aldehydes/benzyl alcohols/styrenes

An efficient, cost-effective, transition-metal-free, oxidative C(sp2)-H/C(sp2)-H cross-dehydrogenative couplingviaa C(sp2)-H bond functionalization protocol for the regioselective direct C-3 acylation/benzoylation of subst

Manganese-Catalyzed Electrochemical Tandem Azidation-Coarctate Reaction: Easy Access to 2-Azo-benzonitriles

A one-pot cascade transformation consisting of an electrochemically driven azidation of 2H-indazole followed by coarctate fragmentation is developed to synthesize the 2-azo-benzonitrile motif. This manganese-catalyzed transformation is external-chemical-oxidant-free and operates at ambient temperature under air. This methodology exhibits good functional group tolerance, affording a broad range of substrate scopes of up to 89% isolated yield. Diverse derivatization of the 2-azo-benzonitrile product resulted in other valuable scaffolds.

Manganese(III) Porphyrin-Catalyzed Dehydrogenation of Alcohols to form Imines, Tertiary Amines and Quinolines

Manganese(III) porphyrin chloride complexes have been developed for the first time as catalysts for the acceptorless dehydrogenative coupling of alcohols and amines. The reaction has been applied to the direct synthesis of imines, tertiary amines and quinolines where only hydrogen gas and/or water are formed as the by-product(s). The mechanism is believed to involve the formation of a manganese(III) alkoxide complex which degrades into the aldehyde and a manganese(III) hydride species. The latter reacts with the alcohol to form hydrogen gas and thereby regenerates the alkoxide complex.