128718-53-6

Basic information

• Product Name: emarginatine B
• Synonyms: emarginatine B
• CAS NO: 128718-53-6
• Molecular Formula: C48H52N2O19
• Molecular Weight: 960.94
• Mol File: 128718-53-6.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 930.9°C at 760 mmHg
• Flash Point: 516.8°C
• Appearance: /
• Density: 1.44g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.613
• CAS DataBase Reference: emarginatine B(CAS DataBase Reference)
• NIST Chemistry Reference: emarginatine B(128718-53-6)
• EPA Substance Registry System: emarginatine B(128718-53-6)

Safety Data

• Hazardous Substances Data: 128718-53-6(Hazardous Substances Data)

Usage

Description

Emarginatine B is a sesquiterpene alkaloid that is a macrolide incorporating a substituted dihydroagarofuran and a pyrindine ring. It is isolated from Maytenus emarginata and exhibits cytotoxicity against human KB cells.

Uses

Used in Pharmaceutical Industry:
Emarginatine B is used as a pharmaceutical compound for its cytotoxic properties against human KB cells. This makes it a potential candidate for the development of treatments for various types of cancer.
Used in Drug Discovery and Development:
Emarginatine B is used as a lead compound in drug discovery and development due to its cytotoxic activity. Researchers can study its structure and properties to design new drugs with improved efficacy and reduced side effects.
Used in Cancer Research:
Emarginatine B is used as a research tool in cancer research to better understand the mechanisms of cytotoxicity and potential applications in cancer treatment. Its study can provide insights into the development of novel therapeutic strategies against cancer.
Used in Natural Product Chemistry:
Emarginatine B is used as a representative example of a sesquiterpene alkaloid macrolide in the field of natural product chemistry. Its unique structure and biological activity make it an interesting subject for chemical and pharmacological studies.

InChI:InChI=1/C48H52N2O19/c1-23-24(2)41(56)67-38-36(66-43(58)30-17-18-32(55)50(9)20-30)40(65-28(6)54)47(22-61-25(3)51)39(68-42(57)29-14-11-10-12-15-29)35(63-26(4)52)33-37(64-27(5)53)48(47,46(38,8)60)69-45(33,7)21-62-44(59)31-16-13-19-49-34(23)31/h10-20,23-24,33,35-40,60H,21-22H2,1-9H3