128753-05-9Relevant articles and documents
Transition-metal-free approach to synthesis of indolines from N-(ortho-chloromethyl)aryl amides and iodonium ylides
Huang, Hui,Yang, Yuan,Zhang, Xiaoyun,Zeng, Weilan,Liang, Yun
supporting information, p. 6049 - 6052 (2013/10/22)
A transition-metal-free method for the synthesis of indolines has been developed. In the presence of K2CO3, the cyclization reaction of N-(ortho-chloromethyl)aryl amides and iodonium ylides proceeded smoothly at room temperature in moderate to good yields.
The acid-promoted reactions of phenyliodonium ylides with substituted anilines and their applications to the synthesis of indoles
Wang, Xianpei,Han, Bing,Wang, Junyan,Yu, Wei
body text, p. 3865 - 3867 (2010/09/17)
The N-substituted anilines 1 react readily with phenyliodonium ylides 2 derived from 1,3-dicarbonyl compounds in the presence of a catalytic amount of BF3·Et2O, forming the C-N coupling products 3, which are precursors for the synthesis of indoles. On the basis of this result, the direct synthesis of indoles from 1 and 2 under thermal conditions and photochemical conditions was explored. The transformations could be achieved in a one-pot way under thermal conditions or in a tandem manner under photochemical conditions.
