128766-97-2

Basic information

• Product Name: 2-[4-(5,5-Dimethyl-2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-ylmethyl)-phenyl]-benzothiazole
• CAS NO: 128766-97-2
• Molecular Weight: 373.412
• Mol File: 128766-97-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[4-(5,5-Dimethyl-2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-ylmethyl)-phenyl]-benzothiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[4-(5,5-Dimethyl-2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-ylmethyl)-phenyl]-benzothiazole(128766-97-2)
• EPA Substance Registry System: 2-[4-(5,5-Dimethyl-2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-ylmethyl)-phenyl]-benzothiazole(128766-97-2)

Safety Data

• Hazardous Substances Data: 128766-97-2(Hazardous Substances Data)

Upstream product

• 24239-18-7 2-<4-(bromomethyl)phenyl>benzothiazole 
• 4090-60-2 5,5-dimethyl-1,3-dioxaphosphorinan-2-oxide 

Relevant articles and documents

Organic phosphorus compounds. IV. Asymmetric 4-(benzothiazol-2-yl)benzylphosphonates as potent calcium antagonistic vasodilators.

Various asymmetric or cyclic ester derivatives of the phosphonic acid moiety in the calcium antagonist fostedil (KB-944) were synthesized. The coronary vasodilator activity of these compounds was assessed by Langendorff's method. Among them, the ethyl isopropyl ester 12 showed the most potent activity, which was comparable to that of fostedil.