128775-92-8Relevant articles and documents
Effects of Substituents on the Chlorination of Methyl 3-Hydroxythiophene-2-carboxylate and on the Reaction of the Resulting Chlorinated Products with Active Hydrogen Containing Compounds
Corral, Carlos,Lissavetzky, Jaime,Manzanares, Ignacio
, p. 315 - 319 (2007/10/02)
The title tandem reactions that produce 5-substituted compounds of methyl 3-hydroxythiophene-2-carboxylate can also be applied with a minor modification to the 4-alkyl and 4-aryl derivatives thereof.On the other hand, 5-alkyl and 5-aryl derivatives that undergo a similar smooth chlorination behave in the second reaction in a different manner.