128790-76-1

Basic information

• Product Name: Guanosine, 2'-deoxy-6-O-(pentafluorophenyl)-N-(trifluoroacetyl)-
• CAS NO: 128790-76-1
• Molecular Formula: C18H11F8N5O5
• Molecular Weight: 529.303
• Mol File: 128790-76-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Guanosine, 2'-deoxy-6-O-(pentafluorophenyl)-N-(trifluoroacetyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Guanosine, 2'-deoxy-6-O-(pentafluorophenyl)-N-(trifluoroacetyl)-(128790-76-1)
• EPA Substance Registry System: Guanosine, 2'-deoxy-6-O-(pentafluorophenyl)-N-(trifluoroacetyl)-(128790-76-1)

Safety Data

• Hazardous Substances Data: 128790-76-1(Hazardous Substances Data)

Upstream product

• 771-61-9 2,3,4,5,6-pentafluorophenol 
• 961-07-9 2'-Deoxyguanosine 
• 961-07-9 2'-deoxyguanosine 

Downstream Products

• 155866-56-1 Toluene-4-sulfonic acid (2R,3S,5R)-3-hydroxy-5-[6-pentafluorophenyloxy-2-(2,2,2-trifluoro-acetylamino)-purin-9-yl]-tetrahydro-furan-2-ylmethyl ester 
• 4546-70-7 2-amino-2'-deoxyadenosine 
• 964-21-6 2-amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)-6-methoxypurine 

Relevant articles and documents

Synthesis of 6-substituted 2'-deoxyguanosine derivatives using trifluoroacetic anhydride in pyridine

Trifluoroacetic anhydride at 0°C reacts with a pyridine suspension of deoxyguanosine to generate a polar intermediate, presumably the corresponding 6-pyridyl derivative. The reaction is complete in less than 15 minutes, and is not accompanied by degradation. From this intermediate a variety of 6-substituted deoxyguanosine derivatives can be obtained, some in excellent yields.