128802-59-5Relevant articles and documents
First Enantioselective Total Synthesis of (+)-Cortisone
Nemoto, Hideo,Matsuhashi, Norikazu,Imaizumi, Mari,Nagai, Mitsuo,Fukumoto, Keiichiro
, p. 5625 - 5631 (1990)
The intramolecular cycloaddition of an olefinic o-quinodimethane, having an optically active oxathiane system as a stereodirecting group, leads enantioselectively to A-nor B-aromatic steroids.This reaction is the key in an enantioselective total synthesis of (+)-cortisone (1).