128812-90-8

Basic information

• Product Name: N¹-Tosyl-N¹-(p-nitrophenyl)-N²-(p-chlorphenyl)acetamidine
• Synonyms: N¹-Tosyl-N¹-(p-nitrophenyl)-N²-(p-chlorphenyl)acetamidine
• CAS NO: 128812-90-8
• Molecular Weight: 443.911
• Mol File: 128812-90-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N¹-Tosyl-N¹-(p-nitrophenyl)-N²-(p-chlorphenyl)acetamidine(CAS DataBase Reference)
• NIST Chemistry Reference: N¹-Tosyl-N¹-(p-nitrophenyl)-N²-(p-chlorphenyl)acetamidine(128812-90-8)
• EPA Substance Registry System: N¹-Tosyl-N¹-(p-nitrophenyl)-N²-(p-chlorphenyl)acetamidine(128812-90-8)

Safety Data

• Hazardous Substances Data: 128812-90-8(Hazardous Substances Data)

Upstream product

• 1956-39-4 4-chloroacetophenone oxime 

Downstream Products

• 734-25-8 N-(4-nitrophenyl)-4-methylbenzenesulfonamide 
• 130117-88-3 N¹-(p-chlorobenzoyl)-N¹-(p-methoxyphenyl)-N²-(p-chlorophenyl)acetamidine 
• 26431-34-5 Ethyl N-(p-chlorophenyl)acetimidate 

Relevant articles and documents

Amidines. I. Hydrolysis of N1-acyl- and N1-tosyl-N1,N2-diarylamidines

In acid hydrolysis of N1-acyl-N1,N2-diarylamidines, a water molecule attacked exclusively the amidine central carbon, and the reaction proceeded in parallel through two pathways. One of them leads to the formation of two N-acylarylamines, and the other leads to the formation of N,N-diacylarylamine and arylamine. Acid hydrolysis of N1-tosyl-N1,N2-diarylamidine was also examined. The results were similar to those of the hydrolysis of N1-acyl-N1,N2-diarylamidines. Alkaline hydrolysis and alcoholysis of N1-acyl-N1,N2-diarylamidines occurred almost exclusively at the amide carbonyl group to give N1,N2-diarylamidines and carboxylic acids or their esters. The effects of structural change and the aryl substituents on the rate and direction of the reaction were examined.