128916-03-0

Basic information

• Product Name: 1H-Pyrrole-1-butanol, b-[bis(phenylmethyl)amino]-, (S)-
• CAS NO: 128916-03-0
• Molecular Formula: C22H26N2O
• Molecular Weight: 334.461
• Mol File: 128916-03-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1H-Pyrrole-1-butanol, b-[bis(phenylmethyl)amino]-, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole-1-butanol, b-[bis(phenylmethyl)amino]-, (S)-(128916-03-0)
• EPA Substance Registry System: 1H-Pyrrole-1-butanol, b-[bis(phenylmethyl)amino]-, (S)-(128916-03-0)

Safety Data

• Hazardous Substances Data: 128916-03-0(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 128916-04-1 (S)-N,N-dibenzylasparagine 
• 161531-12-0 (S)-1-(3-N,N-dibenzylamino-4-hydroxy)butylmethanesulfonate 
• 161531-10-8 (S)-N,N-dibenzyl-2-<1-tert-butyldimethylsilyloxy-4-(1-pyrrolyl)>butylamine 
• 696-59-3 cis,trans-2,5-dimethoxytetrahydrofuran 
• 128916-02-9 (S)-4-amino-2-N,N-dibenzylaminobutanol 
• 152298-86-7 (S)-1-(3-N,N-dibenzylamino-4-tert-butyldimethylsilyloxy)butylmethanesulfonate 

Downstream Products

• 140848-65-3 (S)-7-N,N-dipropylamino-5,6,7,8-tetrahydroindolizine 
• 128915-99-1 1-((R)-1-Phenyl-ethyl)-3-(S)-5,6,7,8-tetrahydro-indolizin-7-yl-urea 
• 128916-01-8 (S)-7-N,N-dibenzylamino-5,6,7,8-tetrahydroindolizine 

Relevant articles and documents

2-Dibenzylaminobutane-1,4-diol: An Effective Chiral Building Block for the Synthesis of 1,2-Amino Alcohols

Regioselective activation and protection of the chiral building block 1, readly available from L-aspartic acid, leads to the key intermediate 8.Employing classical nucleophiles, heterocyclic anions or organocuprates, 8 could be transformed into the displa

NEW AND EFFICIENT SYNTHESIS OF 5,6,7,8-TETRAHYDROINDOLIZIDINES. APPLICATION TO THE SYNTHESIS OF PHARMACOLOGICALLY RELEVANT CHIRAL AMINODERIVATIVES FROM L-ASPARAGINE

A convenient and high yielding cyclization reaction of N-pyrrolylbutyl triflates is shown.The method is applied to afford the potential DA agonists 3, enantiomerically pure from L-asparagine.