128988-10-3Relevant articles and documents
Process for the production of 4,5,6,7-tetrahydrothieno-[3,2-C]-pyridines
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, (2008/06/13)
A process for the production of 4,5,6,7-tetrahydrothieno-[3,2-c]-pyridines of the formula: STR1 Thus, in the case of a 4-oxo-3-piperidine-3-carboxylic acid ester of the formula: STR2 an allyl group is introduced in the 3 position, the ester function in the 3 position is removed, the resultant compound of the formula: STR3 is ionized, reduced to the corresponding aldehyde of the formula: STR4 and with H2 S/HCl in the presence of a metal halide is cyclized to the end product. The synthesized compounds have antithrombotic action.