129046-87-3

Basic information

• Product Name: BOC-ASP-OFM
• Synonyms: n-alpha-tert-butyloxycarbonylasparticacidbeta-fluorenylmethylester;BOC-ASP-OFM;BOC-ASPARTIC ACID-OFM;BOC-L-ASPARTIC ACID ALPHA-9-FLUORENYLMETHYL ESTER;N-ALPHA-T-BUTOXYCARBONYL-L-ASPARTIC ACID ALPHA-9-FLUORENYLMETHYL ESTER;N-(tert-Butoxycarbonyl)-L-aspartic acid 1-(9H-fluorene-9-ylmethyl) ester;N-(tert-Butyloxycarbonyl)-L-aspartic acid 1-(9H-fluorene-9-ylmethyl) ester;N-Boc-L-Aspartic acid 1-(9H-fluoren-9-ylmethyl) ester
• CAS NO: 129046-87-3
• Molecular Formula: C₂₃H₂₅NO₆
• Molecular Weight: 411.45
• Mol File: 129046-87-3.mol
• Article Data: 1

Chemical Properties

• Melting Point: 138-142℃
• Boiling Point: 617.4 °C at 760 mmHg
• Flash Point: 327.2 °C
• Appearance: /
• Density: 1.251
• Vapor Pressure: 4.21E-16mmHg at 25°C
• Refractive Index: 1.576
• Storage Temp.: 2-8°C
• CAS DataBase Reference: BOC-ASP-OFM(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-ASP-OFM(129046-87-3)
• EPA Substance Registry System: BOC-ASP-OFM(129046-87-3)

Safety Data

• Hazardous Substances Data: 129046-87-3(Hazardous Substances Data)

Usage

Description

BOC-ASP-OFM, also known as Boc-Asp-OH, is an aspartic acid derivative with the chemical formula C8H13NO4. It is a white powder and is widely used in various chemical synthesis and peptide chemistry due to its unique properties.

Uses

Used in Pharmaceutical Industry:
BOC-ASP-OFM is used as a building block for the synthesis of various pharmaceutical compounds. Its aspartic acid structure allows it to be incorporated into the development of new drugs, particularly those targeting the central nervous system and other metabolic disorders.
Used in Peptide Chemistry:
In peptide chemistry, BOC-ASP-OFM is used as a key component in the synthesis of peptides and proteins. Its aspartic acid structure provides a versatile platform for the creation of various peptide sequences, which can be used in research and drug development.
Used in Chemical Synthesis:
BOC-ASP-OFM is also used in chemical synthesis for the production of various compounds, including those with potential applications in the fields of materials science, agriculture, and environmental science. Its unique properties make it a valuable reagent in the development of new chemical products.

InChI:InChI=1/C23H25NO6/c1-23(2,3)30-22(28)24-19(12-20(25)26)21(27)29-13-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,24,28)(H,25,26)/t19-/m0/s1

Upstream product

• 13726-67-5 Boc-Asp-OH 
• 24424-99-5 di-tert-butyl dicarbonate 
• 24324-17-2 9-Fluorenylmethanol 
• 91240-51-6 N-tert-butyloxycarbonylaspartic acid anhydride 

Downstream Products

• 939403-15-3 N²-(tert-butoxycarbonyl)-N⁴-[2-acetamido-3,4,6-tri-O-benzyl-2-deoxy-β-D-glucopyranosyl-(1-4)-2-acetamido-3,6-di-O-benzyl-2-deoxy-β-D-glucopyranosyl]-L-asparagine fluorenylmethyl ester 

Relevant articles and documents

An unexpected product from attempted reductive etherification of a silyl alcohol with an aldehyde

Reductive etherification, using BiBr3/Et3SiH, between two modified amino acids, one with a silyl alcohol side chain and one with an aldehyde side chain, gave, not the desired bis-amino acid, but a tetrahydrooxazine, in good yield.