129126-31-4

Basic information

• Product Name: (Z)-N,N-dimethyl-2-(styryloxy)ethanamine
• Synonyms: (Z)-N,N-dimethyl-2-(styryloxy)ethanamine
• CAS NO: 129126-31-4
• Molecular Weight: 191.273
• Mol File: 129126-31-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (Z)-N,N-dimethyl-2-(styryloxy)ethanamine(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-N,N-dimethyl-2-(styryloxy)ethanamine(129126-31-4)
• EPA Substance Registry System: (Z)-N,N-dimethyl-2-(styryloxy)ethanamine(129126-31-4)

Safety Data

• Hazardous Substances Data: 129126-31-4(Hazardous Substances Data)

Upstream product

• 108-01-0 2-(N,N-dimethylamino)ethanol 
• 536-74-3 phenylacetylene 
• 3622-76-2 (2-ethenyloxyethyl)dimethylamine 
• 17763-67-6 Phenyl triflate 
• 591-50-4 iodobenzene 
• 108-86-1 bromobenzene 

Relevant articles and documents

Chelation-Controlled, Palladium-Catalyzed Arylation of Enol Ethers with Aryl Triflates. Ligand Control of Selection for α- or β-Arylation of ethene

Palladium-catalyzed arylation reactions of ethene (1) with a series of aryl triflates were performed under a variety of reaction conditions.In particular, the influence of phosphine ligands and halide additives on regioselectivity were studied.It was found that the chelation-controlled arylation of 1 affords an expedient route for the conversion of phenols into arylacetaldehydes.Alternatively, the same starting materials could be used to synthesize acetophenones by reversing the regioselectivity with bidentate phosphine ligands.

Chelation-Controlled, Palladium-Catalyzed Vinylic Substitution Reactions of Vinyl Ethers. 2-Arylethanal Equivalents from Aryl Halides

The regioselectivity of palladium-catalyzed arylation reactions of a series of nitrogen-containing vinyl ethers is reported.The presence of a β-amino substituent gives a profound influence on regiochemistry.Thus, the arylation of ethene (1c) with a variety of aryl iodides and bromides provides the β-arylation products ethenyl>arenes (3) with at least 95percent selectivity and in good yields.The corresponding arylation of butoxyethene is a nonselective process giving a mixture of α- and β-substitution products.The palladium-catalyzed arylation of 1c constitutes an entry to 2-arylethanals after cleavage of the enol ether.The directing effect of the amino group is discussed in terms of chelation with the intermediate arylpalladium halide.