129170-95-2

Basic information

• Product Name: 3-((S)-1-Octadecyloxymethyl-2-trityloxy-ethoxy)-isoxazole
• CAS NO: 129170-95-2
• Molecular Weight: 653.946
• Mol File: 129170-95-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-((S)-1-Octadecyloxymethyl-2-trityloxy-ethoxy)-isoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-((S)-1-Octadecyloxymethyl-2-trityloxy-ethoxy)-isoxazole(129170-95-2)
• EPA Substance Registry System: 3-((S)-1-Octadecyloxymethyl-2-trityloxy-ethoxy)-isoxazole(129170-95-2)

Safety Data

• Hazardous Substances Data: 129170-95-2(Hazardous Substances Data)

Upstream product

• 38169-74-3 1-O-Octadecyl-3-O-trityl-sn-glycerin 
• 5777-20-8 isoxazol-3-ol 
• 129170-94-1 3-((R)-1-Octadecyloxymethyl-2-trityloxy-ethoxy)-isoxazole 
• 6076-32-0 3-O-Octadecyl-1-O-trityl-sn-glycerin 

Relevant articles and documents

An efficient synthesis of Platelet-Activating Factor (PAF) via 1-o-alkyl-2-o-(3-isoxazolyl)-SN-glycero-3-phosphocholine, a new PAF agonist utilization of the 3-isoxazolyloxy group as a protected hydroxyl

Potent PAF agonists (R)-3a,b were synthesized and converted into PAF. Key steps include Mitsunobu reaction of a chiral secondary alcohol with 3-hydroxyisoxazole as the acidic component, and hydrogenolytic ring cleavage of the resulting 3-isoxazolyloxy gro