129222-32-8Relevant articles and documents
SYNTHESIS OF 7-AMINO-1,2,3,4-TETRAHYDROACRIDINE-9-CARBOXYLIC ACID AND ITS DERIVATIVES. REDUCTION OF NITRO COMPOUNDS UNDER ALKALINE CONDITIONS
Shipchandler, Mohammed T.,Mattingly, Phillip G.
, p. 555 - 561 (2007/10/02)
Condensation of 5-nitroisatin (1) with cyclohexanone in the presence of alcoholic potassium hydroxide, unexpectedly, produced 7-amino-1,2,3,4-tetrahydroacridine-9-carboxylic acid (2) instead of 7-nitro derivative.The general nature of this reaction was shown by substituting several cyclic ketones in this reaction.A radical anion intermediate is proposed to explain this unusual noncatalytic reduction.